British Endocrine Societies Joint Meeting 2002
Harrogate, UK
08 April 2002 - 11 April 2002
British Endocrine Societies
Evaluation of vitamin-D deficiency and other bone biochemical factors in urban population of Tehran - winter 2001
Endocrinology and Metabolism Research Center, Tehran, Iran.
Osteoporosis is one of the most common bone diseases whose complications, morbitidy and mortality impose direct and indirect expenses. Vitamin-D is one of the most important factors in calcium absorption for bone formation. In this study we have evaluated vit-D level and other calcium metabolism indicators in urban population of Tehran.
In a cross-sectional study in winter 2001, 1231 normal persons; 20-69 years, 502 male and 724 female, among urban population of Tehran were selected by random cluster sampling. A questionnaire was filled out and a blood sample was drawn for vit-D, Ca, P, Alk.Ph and PTH for each person. All the confounding factors with vit-D and calcium were considered.
The crude prevalence of vit-D deficiency was 57.1%; 61.6% in women and 50.4% in men (P<0.05). The rate of vit-D deficiency decreased significantly with age (67.1% in 20-29 years vs 41.3% in > 60 years (P<0.05)). 12.1% of persons with vit-D deficiency had hypophosphatemia and 3.6% had hyperphosphatasemia. Also 11% of them had hypocalcemia. 82% of persons with high PTH had vit-D deficiency.
Vit-D deficiency is significant in urban population of Tehran. This deficiency is more prominent in younger women which may be due to life style, diet or air pollution. Complications of vit-D deficiency i.e. osteoporosis and osteomalacia, indicate planning for preventive measures such as food fortification and modifications in life style.
Endocrine Abstracts 3 P6