Endocrine Abstracts

Genetics of ageing in invertebrates

L Partridge

Biology, University College London, London, UK.

Invertebrate model organisms are useful tools for research into ageing because they can be used to identify mechanisms of ageing that are conserved over large evolutionary distances. A picture is emerging of a conserved neuroendocrine axis that regulates reproduction in relation to nutrition, and that causes the rate of ageing to vary as a side-effect. Understanding the mechanisms by which this neuroendocrine axis impacts the ageing process is an important challenge for future work.

Endocrine Abstracts (2002) 4 S9