Endocrine Abstracts

Pulmonary function in Cushing’s disease

T Bayraktaroglu¹, F Kutluturk¹, E Turan², Y Orhan¹ & S Tanyolac¹

¹Istanbul University, Istanbul Faculty of Medicine, Endocrinology and Metabolism, Fatih/Istanbul, Turkey; ²Istanbul University, Istanbul Faculty of Medicine, Pulmonology, Fatih/Istanbul, Turkey.

Numerous clinical manifestations have been described in association with Cushing’s disease (CD). There was no eligible data on pulmonary function tests in CD patients. We aimed to assess pulmonary function test included spirometry in a series of patients with active Cushing’s disease (2 men, 9 women). Mean age, height, weight, body mass index were 36.7±12.6 (range 22–63 years), 156.9±8.4 cm, 74.1±10.7 kg, 29.6±3.8 kg/m², respectively. Spirometric abnormalities (impairments of FEV1, FVC, FEV1/FVC and FEF 25–75 values) were not found, and not different from referans values. In conclusion, there was detected any spirometric impairment in CD patients. It is to need further analyses.

Endocrine Abstracts (2006) 11 P600