Frequency and type of adrenal tumors in our patients
Milica Medic-Stojanoska1, Branka Kovacev-Zavisic1, Tijana Radovanov1, Ivana Bajkin1, Jovanka Novakovic1, Milena Mitrovic1, Dusan Z Tomic1, Nilkola Curic2 & Ljiljana Todorovic-Djilas1
In recent years, adrenal tumors (AT) are no rare disease. They may arise from all zones of adrenal cortex and medulla, benign or malignant, sometimes as metastases of distant malignances. Patients present hormone excess or mass effect, but part of them is clinically silent. The aim of this study was to investigate the frequency, hormonal secretion and pathohistology of AT in our patients lasting years. All patients with AT which are hospitalized in the period from January 1st, 2000. to October 15th, 2006. in our Clinic are included in study. Data of clinical feature, hormonal secretion, imaging and pathohistology of AT are collected in our hospital register of admitted patients and medical records. Patients with AT are divided according to hormonal secretion and pathohistology per years. Linear trend are calculated.
Results: During this 7 years in our Clinic are admitted 102 patients with AT, 65 (63,72%) females and 35 (36,28%) males. It has been 2,38% of all hospitalized patients. Hormonally inactive are presented 64,71%. Patients with hormonally active AT be demonstrated as Cushings syndrome (18,63%), Syndrome Conn (8,82%) and pheochromocytoma (3,92%). According to data of histology and immunohistology after surgery, 89,22% be presented as benign and 10,78% as malignant. Only 5,88% of malignant tumors has been metastases of distant tumors. Linear trend is pointed the increase of incidence patients with AT during period of observation.
Conclusion: The incidence of patients with AT have tendency to increase lasting years in our region. Benign and non-functionally AT are the most common.