Endocrine Abstracts (2010) 22 P273

The effect of diabetes treatment on non alcoholic fatty liver disorder

Sahar Ghareh, Zohreh mousavi & Haleh Rokni

Mashad Medical Science University, Mashad, Islamic Republic of Iran.

Nonalcoholic fatty liver disorder is common among diabetics. Few studies have shown that there is association between type of diabetes treatment and prevalence of NAFLD.

Materials and methods: The prevalence of NAFLD has been evaluated in 236 diabetic patients and the association between type of diabetes treatment and NAFLD was surveyed.

Results: Patients of 63.3% were female. Average age was 50.83±11.21 years. Average weight was 71.95±12.63 kg/m2. Average duration of diabetes diagnosis was 8 years. Average abdominal circumference was 98.54±12.32 cm. Average BMI was 28.1±4.72 kg/m2. Average FBS was 158.32±46.19 mg/dl and average HbA1c was 9.8±6.6%. Six patients (2.6%) were just on diet as diabetes treatment. One hundred and eighty pateints (78.6%) received oral antidiabetics and 23 patients (10%) were on insulin therapy. 20 (8.7%) patients received combination therapy with insulin and oral agents. NAFLD was diagnosed in 38.6% of patients on oral agents and 6.7% of insulin treated patients and 22.2% of patients who received combination therapy.

Conclusion: NFALD was more common in patients who received antidiabetic oral agents than in insulin treated patients.

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