Prolactinoma registry- usefulness of a web tool
Vadim Gavan1, Cristian Taslitchi3, Ruxandra Dobrescu1 & Corin Badiu3
Prolactinoma registry is part of the Romanian national Registry of Endocrine Tumors system (www.renate.ro), which allows the collection and provides epidemiological data concerning the prevalence of age and sex distribution, therapy and its basic results. The centers involved are the medical universities and expertise centers in Romania, centers in which exist enough experience and resources to diagnose, treat and monitor the evolution of these endocrine tumors. The data entered are patients IDs, age and date at diagnosis, the age at which the suggestive symptoms first appeared, tumor size, extension and complications, type of treatment (chemotherapy, surgery and radiotherapy) and its outcomes on parameters such as tumor dimensions, pituitary function and endocrine tumor markers (PRL).
Up to date, over 60 cases are recorded with the following epidemiological data: 74% macroprolactinomas, 26% microprolactinomas, with a sex prevalence of 45% women and 55% men, and an average age at diagnosis of 38,4 years. Prolactinomas were submitted to surgery (17% of all group), and/or radiotherapy (10%). The average follow-up was 50 months.
The access to the site is secured. The network started with 10 centers and will be developed afterwards using already existent hardware resources. This infrastructure is the base of future epidemiological public health surveys in this thematic area. The utility of the web-based registry with secured access is related to the large access and communication capacity beween users of the system.