IN HYPOPHOSPHATASIA (HPP), DEFICIENT ALP can ruin bones, bodies, and lives. Alexion Endocrinology, Diabetes & Metabolism Case Reports

ISSN 1470-3947 (print)
ISSN 1479-6848 (online)

Searchable abstracts of presentations at key conferences in endocrinology

Published by BioScientifica
Endocrine Abstracts (2012) 29 P576 

The relationship between the level of knowledge of physicians on guidelines and the degree of glucometabolic control in type 2 DM patients in Turkey

I Satman1, S Imamoglu2, C Yilmaz1 & on behalf of ADMIRE Study Group3

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Introduction: Clinical practice guidelines on diabetes mellitus (DM) was created by The Society of Endocrinology & Metabolism, Turkey (SEMT). The ADMIRE Project is designed to evaluate the effect of implementation activities to increase physicians’ awareness on guidelines.

Methods: A total of 180 physicians from national representative diabetes clinics kept medical records of 885 T2DM patients for 6 months, without any interference to their routine practice. Then, following awareness activities they kept medical records of 1616 T2DM patients for 6 months. Adherence to guidelines was scored to reach a total adherence to follow-up procedures (TOTAL_ADH_FU) for medical history (HISTORY), physical examination (PHY_EXAM) and laboratory evaluation (LAB_EVAL). Here, baseline results from pre-activity and post-activity periods (PRE and POST) are compared.

Results: PRE and POST data were similar (age 55 vs 57 years, women 62 vs 59% and DM duration 7.1 vs 7.4 years). Treatment preference in PRE and POST were OAD: 46 vs 55%, insulin: 11% in both, OAD+insulin: 25 vs 26%. In PRE, guidelines had been adhered fully for HISTORY in 41% of patients and increased to 85% in POST. The proportions of patients who had PHY_EXAM in full adherence were 9 vs 34% (P<0.001). Patients with LAB_EVAL in full adherence were 30 vs 22% (P<0.001). Only 22.9% of patients were at A1C target (≤6.5%) in PRE, while this figure increased to 28.3% at POST (P=0.014). Proportion of patients at FBG (70–120 mg/dl) and PPBG targets (<140 mg/dl) changed from 17.5 and 12.6–20.7 and 12.8% in POST respectively. Mean A1C levels (%) in PRE and POST were 8.7±2.1 vs 8.4±2.1 (P=0.002). FBG (mg/dl) and PPBG levels (mg/dl) were 191±88 vs 178±77 (P=0.001) and 248±106 vs 240±99 respectively.

Conclusion: Awareness activities significantly increased the proportion of patients at A1C target and decreased both the level of A1C and FBG.

Declaration of interest: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.

Funding: This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.

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