Endocrine Abstracts

Nowadays the human insulines and insuline analogues are used in the treatment of diabetes.

The Advantages of modern insulines

Better glycemic control;

Reduction of hypoglycemia

The reduction of the weight;

Low variability of developing of the complication.

The objective of the survey is to come up to the specific functional benefits about modern insulines through the data analysis, and through researching of

Hemoglobine A1C

The presence og hypoglycemia

Fasting blood glucose.

There were analyzed 40 patients aged 50–80 years in the period of 5 months, who were transferred from a human to modern insulin analogues. Of these, 22 were men and 18 were women.

Conclusion: - The research was done on 40 patients (22 males, 18 females).

- The transfer from human to modern insuline was done on 37 patients although on 3 patients that transfer was done to insuline glargine.

The reason of this transfer was the enormous increasing of their weight.

- According to the hypoglycemias there was reduction of their number despite their glycemic control.

Besides this only two patient complained on the major hypoglycemia and the main reason for this was not taking their meal during the day.

The measurement and the values of AB A1C showed that only 5 patients had hemoglobine A1C higher then 9.

Fasting blood glucose refered from 6.5 mmol/l to 7.9 mmol/l.

Keywords: insuline analogues, Hemoglobine A1C, hypoglycemia, hyperglycemia.

Declaration of interest: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.

Funding: This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.