Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2016) 41 EP1108 | DOI: 10.1530/endoabs.41.EP1108

ECE2016 Eposter Presentations Thyroid cancer (81 abstracts)

Ultrasonographical, clinical and histopathological features of 1264 nodules with papillary thyroid carcinoma and microcarcinoma based on tumor size

Neslihan Cuhaci 1 , Husniye Baser 2 , Oya Topaloglu 1 , Didem Ozdemir 1 , Aydan Kilicarslan 3 , Reyhan Ersoy 1 & Bekir Cakir 1


1Department of Endocrinology and Metabolism, Ankara Yildirim Beyazit University School of Medicine, Ankara, Turkey; 2Department of
Endocrinology and Metabolism, Atatürk Education and Research Hospital, Ankara, Turkey; 3Department of Pathology, Ankara Yildirim Beyazit University School of Medicine, Ankara, Turkey.


Introduction: In recent years, due to the improvements in ultrasonography (US), it has become possible to gain more information about the papillary throid carcinoma (PTC) and papillary tyroid microcarcinoma (PTMC). However, whether PTC and PTMC exhibit the same ultrasonographic features and behave same features is controversial. We aimed to evaluate the patients diagnosed with PTC and PTMC in terms of clinical, ultrasonographical (US) and histopathological features and their relationships with tumor size.

Methods: We retrospectively evaluated 881 patients who underwent thyroid surgery between 2007 and 2014 in our clinic and diagnosed with PTC histopathologically were enrolled the study. Demographic characteristics, US findings and histopathological features were evaluated.

Results: In total, 1264 nodules were identified in the 881 patients. The incidentality rates were higher in the PTMC group and also in the ≤5 mm group. In total multifocality rate was 32.9%, and it was significantly higher in PTMC group than the PTC group. PTC and >5 mm PTMC groups compared to PTMC and ≤5 mm groups respectively, were more aggresive histopathological features

Conclusion: Since the incidentality rates were found significantly more common in our patients with PTMC and those with ≤5 mm, ultrasonographic features of the nodules should be evaluated carefully and for cases which are suspicious with US, US-guided fine needle aspiration biopsy (FNAB) should be considered in order to make the correct treatment strategy. Also our study revealed that PTC and >5 mm PTMC groups compared to PTMC and ≤5 mm groups respectively, have more aggresive histopathological features.

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