Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2016) 41 EP143 | DOI: 10.1530/endoabs.41.EP143

ECE2016 Eposter Presentations Calcium and Vitamin D metabolism (61 abstracts)

Sensitivity of localization studies performed by various radiologists whom are not precisely experienced in the evaluation parathyroid lesions

Pinar Sisman 1 , Ozen Oz Gul 1 , Coskun Demirtas 2 , Aybuke Muti 2 , Onur Elbasan 2 , Ozlem Saraydaroglu 3 , Soner Cander 1 , Canan Ersoy 1 & Erdinc Erturk 1


1Department of Endocrinology and Metabolism, Uludag University Medical School, Bursa, Turkey; 2Department of Internal Medicine, Uludag University Medical School, Bursa, Turkey; 3Department of Pathology, Uludag University Medical School, Bursa, Turkey.


Objectives: Preoperative imaging studies are being commonly used in primary hyperparathyroid patients to increase cure rate and to decrease complication rate of surgery. In this study we correlated the surgical outcomes with localization studies performed by various radiologists.

Method: A total of 174 patients with primary hyperparathyroidism in which healing of hypercalcemia achieved by parathyroidectomy were evaluated retrospectively. Since our hospital is a teaching hospital numerous radiologists were trained during the period of 2005 to 2015. For that reason preoperative cervical ultrasound (US) and sestamibi scan (MIBI) had been carried out by various examiners. According to laterality, imaging studies were categorized as true or false positive, or true or false negative, and sensitivity and specificity rates were calculated.

Results: A total of 184 lesions were excised from 174 patients (162F/27M, 52.7±12.2 years of age). US and MIBI localization studies matched in 74 and 108 patients, respectively. False positive, and false negative results for US was 3.3 and 68.4% while false positive and false negative results for MIBI was 4.3 and 35.3%. We calculated very similar results for specificity of US and MIBI 95.9 and 95.0%, but sensitivity results were really far from satisfaction with 45.9% for US and 62.4% for MIBI.

Conclusion: Experience of examiner in parathyroid imagining effects primarily sensitivity but not specificity. Parathyroid surgeon should be well practiced to perform ultrasonographic evaluation by himself before operation.

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