Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2016) 41 EP168 | DOI: 10.1530/endoabs.41.EP168

1Endocrinology Department, Virgen de la Victoria University Hospital, Malaga, Spain; 2Biomedical Research Laboratory, Endocrinology Department, IBIMA, Malaga, Spain; 3Badolatosa Primary Care Centre, Seville, Spain; 4Cruz de Humilladero Primary Care Centre, Malaga, Spain.


Objectives: To study vitamin D deficiency in a cohort of obese males and to evaluate associated clinical and biochemical characteristics.

Methods: Case-control study which included obese (defined by a BMI ≥30 kg/m2) males. Vitamin D deficiency was defined as vitamin D levels <20 ng/ml. Estimation of vitamin D status was determined in serum using a commercially available enzyme- immuno-assay designed to measure 25-OH Vitamin D concentrations in serum or plasma (Immundiagnostik, Quantikine, Bensheim, Germany).

Results: 225 obese males were included in the study. Prevalence of vitamin D deficiency was 51.3%; mean vitamin D levels was 13.8 ng/ml in the group with vitamin D deficiency and 27.3 ng/ml in normal vitamin D status group (P<0.001 for comparison). No differences in age (36.0 vs 37.7, P=0.1), insulin resistance (measured by HOMA-IR index) (5.2 vs 4.3, P=0.11), calcium levels (9.06 vs 9.0 mg/dl), PTH levels (46.1 vs 44 pg/ml, P=0.35) or HbA1c (5.4 vs 5.4, P=0.6) was found between patients with or without vitamin D deficiency, respectively. Patients with vitamin D deficiency were more obese (BMI 40 vs 37.4, P=0.04) and had higher levels of PCR (7.5 vs 5.3 mg/l, P=0.01).

Conclusions: Vitamin D deficiency affects to ~50% of obese males. These patients tend to be more obese and have higher PCR levels than patients with normal concentrations of vitamin D.

Article tools

My recent searches

No recent searches.