Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2018) 56 S23.3 | DOI: 10.1530/endoabs.56.S23.3

ECE2018 Symposia Pre-diabetes (3 abstracts)

Treatment of Pre-Type 2 Diabetes

Riccardo Bonadonna


Italy.


Pre-Type 2 Diabetes has not a commonly shared definition. In this talk, the term will be used to indicate people with impaired fasting glucose and/or impaired glucose tolerance and no evidence of pancreatic beta cell autoimmunity. These people are known to be at increased risk of cardiovascular disease/mortality, yet it it is still unclear whether this abnormal risk can be accounted for by the concomitant presence of well recognized risk indicators/factors, most of which are collected under the umbrella of the Metabolic Syndrome. By the same token, there is no known specific treatment of this increased risk beyond the therapies used for the single known risk factors (therapeutic lifestyle changes, therapies for obesity, dyslipidemia, hypertension, etc.). Type 2 Pre-Diabetes also is a high risk condition for type 2 diabetes. Several clinical trials have documented that primary prevention (and often reversal to normal fasting glucose and normal glucose tolerance) of type 2 diabetes in these people can be achieved by as diverse tools as therapeutic lifestyle changes, or metformin, or acarbose, or pioglitazone, or bariatric surgery etc. In many instances, it is somewhat unclear whether the improvement should be ascribed to the effects of early treatment of diabetes or to a genuine modification of the natural history of the disease. However, beneficial effects may be detected even several years after quitting the preventative intervention. Although therapeutic lifestyle changes should be the mainstay of type 2 diabetes primary prevention, they are not as effectively implemented in standard clinical care as they should, possibly owing to costs and a number of hurdles that both the patient and the health care provider need to overcome. Nevertheless, the agenda of type 2 diabetes worldwide will never meet the challenge of type 2 diabetes pandemics without vast and effective programs of primary prevention.

Volume 56

20th European Congress of Endocrinology

Barcelona, Spain
19 May 2018 - 22 May 2018

European Society of Endocrinology 

Browse other volumes

Article tools

My recent searches

No recent searches.

My recently viewed abstracts

Authors