Endocrine Abstracts

Endocrinopathy is common in patients with HIV and presents a distinct series of challenges. Polypharmacy is common (both of prescribed and non-prescribed drugs) with the potential for drug-drug interactions and endocrine adverse effects of longterm medication. Structural pathology is also commoner than in the general population with the potential for both tumours and atypical infections affecting endocrine organs. Altered binding proteins are common, particularly high SHBG, affecting interpretation of total hormone assays. Autoimmune endocrinopathy is also common, particularly with the immuno-reconstitution that occurs in the months after commencing anti-retroviral therapy. I will share some cases, experience gained and tips from working with a large HIV unit.