Endocrine Abstracts

Introduction: We present two pregnant women who were referred to obstetric endocrinology service with polyuria and polydipsia. They were investigated and treated for diabetes insipidus (DI). In both cases, the underlying pathophysiology was ADH insufficiency secondary to autoimmune lymphocytic hypophysitis. There are currently no consensus guidelines on the diagnosis of DI during pregnancy. These cases highlight best practice and endorse MDT management of chronic hypopituitari...

Background: The practice of endocrinology requires the support of good laboratory services in order to make accurate diagnosis of many endocrine disease. Many endocrine disorders appear rare in our country because of lack of reliable laboratory services. The following cases illustrate this frustration.Case 1: A 39-year old caterer, known hypertensive but diagnosed diabetic recently when she developed a non-healing left foot ulcer and subsequent gangrene ...

A 25 year-old female Polytechnic student who presented at the emergency department with a 5-day history of high grade fever with chills and rigor, headache, generalized body weakness, postpandrial vomiting, epigastic pain and passage of melena and feeling of cramps in her hands and feet. Had no history of PUD but had used NSAIDS for pains and the cramps.Her RBS was 155 mg/dl. Genotype unknown. LMP 6/4/17Physi...

A 25 year-old female Polytechnic student who presented at the emergency department with a 5-day history of high grade fever with chills and rigor, headache, generalized body weakness, postpandrial vomiting, epigastic pain and passage of melena and feeling of cramps in her hands and feet. Had no history of PUD but had used NSAIDS for pains and the cramps.Her RBS was 155 mg/dl. Genotype unknown. LMP 6/4/17Physi...

26-year-old female lawyer who was first diagnosed to have Grave’s disease in our Endocrinology clinic, when she presented with palpitations, protruding eye balls, progressive weight loss good appetite, heat intolerance and a small goiter and confirmatory TFT results. She was controlled with (and maintained on) 10 mg of carbimazole. She also had flesh-colored swellings, with areas of hyperpigmention and induration on her shins, as well as hyperpigmented patches on her ankl...

A 54 year-old businesswoman who has been diabetic for 6 years and had a history of PUD. She was referred following complaints of increasing hyperpigmentation of her palms, feet and old scars. She also had a boil on her back, significant weight loss, poor appetite and a slight non-productive cough.She was transfused with two pints of blood a month earlier at a private hospital when her PCV was found low. She is not hypertensive. Her drug history included ...

Introduction: Hypoglycaemia is a common and serious complication of diabetes treatment especially in patients who do not have knowledge of the condition and personal glucose metres. Patients with very good drug compliance are at greater risk of developing hypoglycaemia. Sometimes hypoglycaemia among patients on insulin therapy could be symptomatic or asymptomatic. The present study is aimed at measuring the determinants and predictors of hypog...

Background: Hypoglycaemia is a life-threatening condition commonly encountered in emergency department (ED), mainly among individuals with diabetes on insulin or oral hypoglycaemic agents (OHA). Hypoglycaemia in non-diabetic individuals is not a common condition and its often a diagnostic challenge for clinicians especially when presented in an unusual way. Although it does not seem to be a cardiac emergency feature, various electrocardiograph...

Introduction: Hypoglycaemia is a common and serious complication of diabetes treatment especially in patients who do not have knowledge of the condition and personal glucose metres. Patients with very good drug compliance are at greater risk of developing hypoglycaemia. Sometimes hypoglycaemia among patients on insulin therapy could be symptomatic or asymptomatic. The present study is aimed at measuring the determinants and predictors of hypog...

Background: Hypoglycaemia is a life-threatening condition commonly encountered in emergency department (ED), mainly among individuals with diabetes on insulin or oral hypoglycaemic agents (OHA). Hypoglycaemia in non-diabetic individuals is not a common condition and its often a diagnostic challenge for clinicians especially when presented in an unusual way. Although it does not seem to be a cardiac emergency feature, various electrocardiograph...