Endocrine Abstracts

Introduction: Thyroid dysfunctions and autoimmunity may concur in the pathogenesis of hemostasis abnormalities. Hashimoto’s thyroiditis (HT) is a frequently chronic autoimmune disease in thyroid gland. The aim of our study were to comparison the hemostatic parameters in patients with HT and control subjects.Method: A total of 52 women were evaluated. Age, TSH, free T3, free T4, anti M, anti Tg, TAFI, TFPI, PAI-1, tPA, PF-4, fib...

Primary thyroid lymphoma is an uncommon malignancy; it accounts for <2% of all extranodal lymphomas and <5% of all thyroid malignancies.Case report: A 52-year-old male patient who was known to have a nodule in his thyroid gland for many years presented with instantaneous enlargement of his existing nodule and with appearance of ipsilateral cervical lymphadenopathy. On thyroid ultrasonography, a giant nodule of 38.4×31.6×45.5 mm size, an...

Background: Adrenocortical carcinoma (ACC) is a very rare but typically aggressive malignancy. About one to three quarters of ACC is functioning with excess hormonal production.Case: A 44-year-old female patient was admitted to out-patient clinic with obesity, oligomenorrhea and abdominal pain. She had central obesity, buffalo hump, and palpable flank mass. Hypertension, transient ischemic attack, and epilepsy history was present.S...

Introduction: Ectopic adrenocorticotropic hormone (ACTH) secretion is a less common cause of Cushing syndrome(CS) and is seen in 5 to 10% of patients with endogenous hypercortisolism. The most common types are bronchial carcinoids and small cell lung carcinoma. However, in approximately 10–20% of the cases, overt tumor cannot be found. Here, we described two patients with catastrophic hypercorticolism associated with ectopic CS and who were treated with bilateral adrenale...

Aims: Impact of gestational diabetes mellitus on the coagulation system, dynamics involved at a pathophysiological level and the exact mechanism remain unclear.To evaluate association between diabetes-related parameters and haemostatic factors in order to search for a tendency of thrombosis in gestational diabetes mellitus.Methods and Material: Nineteen pregnant women who had gestational diabetes mellitus, 16 healthy pregnant and 1...

Polycystic ovary syndrome (PCOS) is a common hormonal, metabolic and reproductive disorder characterized by androgen excess, ovulatory dysfunction and polycystic ovaries. The phenotypic presentation might differ between referral and unselected populations and varies within an individual over time and between individuals of different ethnic and geographic regions. Women with PCOS have increased prevalence of prediabetes and diabetes and have multiple risk factors for cardiometa...

Obesity and type 2 diabetes are common and complex traits that are closely related and the term ‘diabesity’ is being used for the twin global epidemic of these two disorders. PCOS is another common and complex disorder characterized by androgen excess, oligo-anovulation and polycystic ovaries on ultrasound. PCOS is linked with both obesity and type 2 diabetes. Although obesity and type 2 diabetes are not universally observed in PCOS, many women with PCOS are obese an...

Hirsutism, defined as excessive male-pattern terminal hair growth in females, affects about 5–10% of the women of reproductive age depending on the population studied and the method used to determine its presence. Hirsutism is the primary clinical diagnostic criterion of hyperandrogenism. Hyperandrogenism can result from increased androgen production and/or increased sensitivity of hair follicles to androgens. The presence of hirsutism in women can lead to significant psy...

Reproductive systems of the Mongolian gerbils are controlled by the photoperiod but body weight is independent of photoperiod. Food intake has an effect on reproduction and gerbils are very sensitive about food intake. Leptin hormone has controls on both food intake and body weight. Finding a link between changes in feeding behavior and reproductive activity in relation to obesity-related issues will play an important role. In this study, three groups were established; a) food...

Hirsutism, development of terminal body hair in women in unexpected areas, may result from different etiologies; 4.3% being nonclassical congenital adrenal hyperplasia (NCCAH) and acromegaly being one of the rarests. We here present a severe hirsutism case with acromegaly and NCCAH.Case: A 30-year-old woman with headache and visual field abnormalities was consultated by our clinic about her cranial imaging revealing a macroadenoma in pituitary localizati...