Endocrine Abstracts

Introduction: Sheehan syndrome (SS) is caused by postpartum necrosis of the pituitary gland, associated with significant haemorrhage during or after delivery. It is rare in developed countries, but still frequent in underdeveloped ones. We present a rare presentation of this syndrome.Clinical case: A 48 years old black woman presented at the emergency department for long term fatigue and dyspnea that worsened a few days before. Her physical examination r...

Giant prolactinomas are uncommon, with some individual case reports described in the literature, but with few series documenting treatment outcomes. They represent a therapeutic challenge, since restoring normoprolactinemia, eugonadism and reducing tumour size may not be realistic goals. Specific complications may also arise during treatment that change the initial management plans. The authors describe a case of a 28-year-old male with visual impairment and behavioural change...

This prestigious prize is intended for established workers in the field of basic and clinical neuroendocrinology and is generously supported by Ipsen. This year’s recipient is Prof. Carlos Dieguez. The prize will be presented as part of the ECE 2015 opening ceremony where Prof. Dieguez will deliver his lecture. Prof. Dieguez will also deliver two other lectures at future ESE scientific meetings. Further information can be found at <a href="http://www.ese-hormones.org/priz...

Introduction: Type 1 Gastric neuroendocrine tumors account for 70 to 80 percent of all gastric neuroendocrine tumors (G-NETs) and they are found more commonly in older adults, particularly women. They are associated with autoimmune metaplastic atrophic gastritis (AMAG) with or without pernicious anemia. They are usually smaller than 1 cm and often multiple. Our goal is to describe different characteristics of type 1 G-NETs and to study possible prognostic factors related to th...

Introduction: Neuroendocrine tumors (NETs) constitute a very heterogeneous group of rare neoplasms, although their incidence has increased in recent years. We describe its evolution and survival.Methods: Retrospective study. All patients with histopathological diagnosis of GEP-NETs performed at the HCSC between 2000 and 2016 were selected, data from the medical history were included. Statistical analysis were done with SPSS.Results...

Introduction: Adrenocortical carcinoma (ACC) is a rare and aggressive tumor that accounts for 0.2% of cancer-related deaths. Case series and prospective studies are very limited due to its low prevalence. Current knowledge is based primarily on the opinions of experts in specialized units. The aim of this study is to perform a descriptive analysis of the management and prognosis of patients with ACC in HCSC in the last 20 years.Material and methods: Eigh...

The question on how cells, tissues and organisms are able to detect energy/nutrient availability has been the focus of research for many years. Data gleaned recently have identified different nutrient-sensing circuits implicated in the regulation of different homeostatic process. Furthermore, there has been a steady increase in our knowledge regarding the cellular and molecular mechanisms involved in nutrient detection and integration. In particular, this has allowed for a bet...

Introduction: Type 1 Gastric neuroendocrine tumors account for 70 to 80 percent of all gastric neuroendocrine tumors (G-NETs) and they are found more commonly in older adults, particularly women. They are associated with autoimmune metaplastic atrophic gastritis (AMAG) with or without pernicious anemia. Endoscopically, they are usually smaller than 1 cm and often multiple. These tumors usually present a non-aggressive evolution. Our goal is to approach the presence of risk fac...

Introduction: The multidisciplinary approach of the patients with GEP-NETs is very important, having a fundamental role the participation of the endocrinologist.Methods: Description of cases of GEP-NETs followed in the Service of Endocrinology of the SCCH from 1990 to 2016.Results: 95 patients were included, 53.7% were males, age 61.2 years (IR: 50.5–73.5). The diagnosis was incidental in 53.8%. 27.6% presented clinical secret...

Current indications for adjuvant Radioactive Iodine (RAI) in low- and intermediate-risk differentiated thyroid cancer (DTC) are controversial. At the same time, there is universal consensus for personalized DTC management according to individual patient needs, as there does not appear to be a ‘‘right’’ way to treat patients with DTC. According to the Martinique Principles 1, adjuvant RAI treatment has many goals, including: initial stagi...