Endocrine Abstracts

Introduction: Thyroid dysfunction, whether overt or subclinical, has a significant effect on the cardiovascular system. On the other hand, fluctuation of thyroid hormones within the normal range has been associated with long-term health risks, and might have an impact on the vasculature. This study assessed the effect of thyroid hormones on surrogate markers of arterial structure and function in a sample of euthyroid postmenopausal women.Methods: This cr...

Introduction: In the Covid-19 era mass media present people worldwide, including in Greece, to transiently flock to green spaces and parks. A study from the Western United States in 2020, indicated that indeed, park visitation may have increased by 20% compared to baseline (the immediate pre-Covid-19 period). The Google mobility index (GMI) is based on location data/visits - from smartphone users - to various areas; among areas of mobility the GMI can focus specifically on vis...

Introduction/Aim: The diagnosis and management of hypothyroidism in pregnancy is a domain of shifting paradigms, with changes in guidelines, which may have led clinicians to confusion or angst (Endocrine Today; October 2019). Since sentiment analysis (SA) of medical texts can be implemented (Artificial Intelligence in Medicine 2015; 64: 17–27) we sought to use SA regarding this clinical issue.Materials/Methods: We collected the English language abst...

Introduction: Regardless of the fact that the incidence of thyroid cancer has increased significantly in recent years, the simultaneous occurrence of multiple tumors in one thyroid gland is still a rare phenomenon. These tumors have the morphology, either of a single mass with mixed histological features, or of a single lesion consisting of two distinct cell-populations, or of two different tumors between which normal thyroid tissue is interposed. Various theories have been pr...

Context: Prior studies of children with endogenous Cushing syndrome (CS) have identified cognitive decline despite reversal of brain atrophy after remission as well as residual impairment of quality of life measures. Although parental observations support personality changes with CS, significant psychopathology has not been described. We investigated the feasibility of using paediatric Patient-reported outcomes (PROMIS) using a computer interface to assess patient perception o...

Background: Adrenal incidentalomas (AI) have an increasing prevalence during last decades, probably due to the extended use of new imaging techniques and longer life expectancy. Adrenal hormonal hypersecretion, even subclinical, is probably related to cardiovascular disease (CVD).Methods: We evaluated 100 patients with adrenal masses, incidentally discovered in imaging techniques performed for non adrenal disorders (67 Female, 33 Male, mean 58.1±12....

Background: Carney complex (CNC) is a rare multiple neoplasia syndrome, its commonest endocrine manifestation being ACTH-independent Cushing’s syndrome, histologically characterized by primary pigmented nodular adrenocortical disease (PPNAD). There is significant genetic and phenotypic heterogeneity, but deletions at 17q24.2 are rare. We describe the particular characteristics of a patient with a microdeletion in this area.Case report: A 37-year-old...

Introduction: The assessment of the glycemic regulation of patients with Type 1 Diabetes Mellitus is necessary, in order to design an individualized treatment plan, to control the complications resulting from hyper- or hypoglycemia. For this purpose, we use HbA1c, continuous glucose monitoring (CGM) with TIR (time in range), or blood glucose monitoring (BGM). However, none of the above, can be applied without the cooperation of the patient, which for various reasons, often bec...

Introduction: Adrenal Cushing’s syndrome accounts for 15-20% of all the causes of endogenous hypercortisolism, mainly due to unilateral adenomas and adrenal cancer. Approximately 9-17% of patients with ACTH-independent Cushing’s syndrome have bilateral adrenal adenomas. Subsequently, their management is quite demanding. The main difficulty lies in distinguishing between a functional and a non-functional adrenal mass, since this cannot be reliably achieved by routine ...

Introduction: Lactation is a period of particular importance regarding the management of glycemia in women with Diabetes Mellitus type 1 (DM1), the aim being to prevent hypoglycemia during breastfeeding. The purpose of this study was to investigate the variation of insulin requirements during lactation in comparison with pre-pregnancy levels in women with DM1 and to find potential correlation factors.Materials-methods: We conducted a retrospective case f...