Endocrine Abstracts

Background: Familial chylomicronemia is a rare disorder of lipoprotein metabolism characterized by severe fasting hypertriglyceridemia. We present here a case of severe familial chylomicronemia with multiple complications.Case presentation: A 35-year-old Tunisian woman was suffering from chylomicronemia (Fredrickson type I hyperlipoproteinemia) since the age of 10 years old. Her dyslipidemia was caused by a lipoprotein lipase deficiency. Since her childh...

Introduction: The prevalence of Gestational diabetes mellitus (GDM) has been increasing recently. Educating women of childbearing age about GDM, its risk factors and complications may help its prevention and improve its outcomes. Hence, the aim of this study was to assess the level of knowledge of Tunisian pregnant women about gestational diabetes, its risk factors and its consequences.Methods: We conducted a cross-sectional study among pregnant women wh...

Aim: Thyroid disorders are very common in women of reproductive age. The aim of this study was to determine the prevalence of different biological thyroid disorders during gestational diabetes mellitus (GDM).Methods: This was a retrospective observational study carried out between March and June 2017 in the day hospital of the National Institute of Nutrition. Pregnant women referred for the management of GDM and who have no history of prior thyroid disor...

Objective: Dyslipidemia represents an added factor of cardiovascular risk for patients with diabetes. The objective of this work was to study the characteristics of dyslipidemia in a group of patients with diabetes.Methods Cross-sectional study including a group of patients with diabetes associated with dyslipidemia, during a period of 6 months, admitted in the day hospital unit of the National Institute of Nutrition of Tunis. The data was collected by c...

Aim: The aim of our study was to describe the lipid profile of Tunisian women after pregnancy with gestational diabetes mellitus (GDM) and to analyze the influence of maternal age, insulin requirement and postpartum glycemic status on lipoproteins changes after pregnancy.Methods: We conducted a cross-sectional study among pregnant women who were referred to the national institute of nutrition for management of GDM. The lipid profile included total choles...

Aim of the studyTo identify the factors predicting insulin need in women with Gestational Diabetes Mellitus (GDM).MethodsIt was a retrospective study conducted in the National Institute of Nutrition between January 2018 and January 2019. Pregnant women referred for the management of GDM were included (n = 1000).GDM was defined according to the World Health Organisation as a glucose intolerance of var...

Background: Metformin is the most known oral glucose-lowering medications. It is considered to be the optimal first-line treatment for patients with type 2 diabetes mellitus.GoalThe aim of the study was to describe the clinical and biological profile of patients with type 2 diabetes mellitus treated with metformin.Methods: This was an observational study conducted among 57 patients with type 2 diabetes mellit...

Introduction: Glycemic control in diabetic patients undergoing hemodialysis is difficult to achieve because of the high glycemic variability in this population. The aim of our study was to assess the glycemic profile, using the continuous glucose monitoring system ‘CGMS’, in a group of insulin-treated diabetic patients on hemodialysis.Methods: We conducted a descriptive, evaluative, longitudinal study involving insulin-treated diabetic patients...

Objective: The objective of our study was to identify maternal and biological factors associated with the use of insulin therapy in patients with GDM.Methods: Retrospective study including 100 pregnant women followed up for gestational diabetes during the year 2021. Information was collected from medical records and supplemented, if necessary, by telephone interviews with the patients.Results: The mean age of the patients was 32.7&...

Introduction: Fasting during Ramadan is an obligatory practice for adult Muslims. Although exemptions exist in certain conditions,including diabetes, the majority of diabetic patients fast despite this concession with the risk of complications mainly hypoglycemic accidents. The aim of this study is to establish the relationship between hypoglycemic accidents and drug treatment, therapeutic education, clinical and biological characteristics of tunisian diabetic patients during ...