Endocrine Abstracts

A 66-year-old female patient presented post-menopausal with vaginal bleeding. She was on Oestrogen cream. The US showed a right ovarian cyst. The C125 was normal, and the uterine biopsy showed no malignancy. The bleeding continued and she was reviewed 4 months later. The MRI shows evidence of uterine adenomyosis. The right ovarian cyst is likely to represent a right ovarian endometrioma (32 × 28 × 30 mm). She was referred to the endocrine clinic for as increased hair...

A 76-year-old lady was admitted to a Spanish Hospital with vertigo and dizziness. Investigations revealed hypercalcaemia and a right adrenal mass on an MRI abdomen. On returning to the UK, she was referred to endocrinology. Additional symptoms included fatigue, memory loss and some leg weakness over the preceding months. She was noted to be hypertensive, controlled on Amlodipine 5 mg od. Investigations revealed an elevated serum corrected calcium of 2.85 mmol/l and serum PTH r...

Background: Severe hyponatremia can be associated with oxytocin infusion. The incidence of hyponatraemia after oxytocin is around 5%. There are reported cases of serious neurological complications including seizures, coma and maternal death.Case report: A 37-year-old female with known partial central diabetes insipidus following a head injury was established on Desmopressin nasal spray 10 mg twice a day. She had an uneventful pregnancy on the same dose. ...

Aim: Progesterone is thought to be associated with hyperemesis gravidarum (HG). Pregnancies in which progesterone is administered for luteal phase support do not exhibit an increased incidence of HG, suggesting that high progesterone levels alone do not cause HG. The aim of the present study was to evaluate the therapeutic role of progesterone therapy as a new modality in the management of hyperemesis.Subjects: In total, 40 Egyptian women below 40 years ...

Chronic elevation of saturated fatty acids (SFAs) and glucose (Glc) appears to activate an inflammatory response; compounded by habitual feeding. Restoration of physiological SFAs and Glc levels post-prandially may not attenuate the original insult; a concept termed ‘metabolic memory’. Therefore we investigated (1) the effect of chronic and oscillating SFAs and Glc on the inflammatory pathway in human abdominal subcutaneous (AbdSc) adipose tissue (AT) and adipocytes ...

Background: Pituitary abscess is a rare entity which is often not suspected in pituitary lesions differential diagnoses; arising de novo or as a consequence of sinus infection, meningitis, or haematogenous spread. The diagnosis is challenging and mostly made during surgery.Case Report: A 54-year-old male patient presented with 3 days of severe headaches, vomiting, and left eyelid drooping. He was afebrile, BP 90/61mmHg, and had a left third nerve palsy w...

Introduction: Parathyroid cysts (PCs) are uncommon lesions. They represent less than 0.5% of parathyroid lesions. Cysts are divided into two groups, functional and non-functional, in relation to their hormonal characteristics. Non-functioning ones make up 80 – 90% of PCs.We discussed three cases of non-functioning parathyroid cysts that we surgically excised.Methods: We report 3 cases of non-functioning PCs treated in our department.<p class="ab...

Introduction: Anaplastic thyroid carcinoma (ATC) is rare. This highly aggressive malignant tumor accounts for 2 – 3 % of all thyroid gland neoplasms. ATC continues to be one of the deadliest diseases worldwide and carries a very poor prognosis. The aim of this study was to describe the treatment modalities of ATC and its prognostic features.Methods: A retrospective study of patients with ATC treated in our department between 2004 and 2021.<p cla...

Background: Thyroid nodules found in patients with Graves’ disease have a higher likelihood of being malignant. Management of these association is controversial.Objectives: To discuss clinical and therapeutic features of this association.Materials and methods: We report three cases of thyroid cancer occurring in Graves’ disease, treated surgically at our department.Results: There were three patients...

Objective: Our aim is to describe the epidemiological, clinical and paraclinical features of intrathyroidal parathyroid cysts (PCs). Materiel and Methods : We report 2 cases of intrathyroidal PC treated in our ENT department. Results : We report 2 cases of non-functioning intrathyroidal PCs: 2 women (22 and 45 years old). They were referred to our department for anterior neck mass lasting for an average of 13 months. They had no co...