Searchable abstracts of presentations at key conferences in endocrinology

Endocrine Abstracts

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ea0002sp4biog | Society for Endocrinology Jubilee Medal Lecture | SFE2001

Society for Endocrinology Jubilee Medal Lecture

Besser M

Michael Besser, St Bartholomew's and Royal London School of Medicine and Dentistry, London, UK AbstractProfessor Michael Besser qualified in medicine in 1960 at the Medical School of St Bartholomew's Hospital, and then undertook a number of junior medical posts there and at the Royal Postgraduate Medical School and the Royal Brompton Hospital. He started his academic work initially as junior lecturer in therapeutics i...
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ea0011p782 | Thyroid | ECE2006

Correlation between endogenous thyroxin and A, G, and M immunoglobulins in dysthyreosis

Laszlo A , Pascanu I , Gliga C , Schiopu A , Laszlo M

Introduction: The thyroid is a multifunctional endocrine gland which, by its hormones, affects all the organs, metabolisms and nonspecific defence of the body. The aim of this study is to establish if endogenous thyroxin (FT4) is involved in the nonspecific defence of the organism.Material and methods: 94 patients were included in the study, 47 with hyperthyroidism and 47 with hypothyroidism, 81 women, 13 men aged 7–78. FT4 was...
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ea0049ep598 | Diabetes therapy | ECE2017

The hypolipidemic and hepatoprotective efficacies of a fixed-dose combination of essential phospholipids with methionine (EPL+M) during atorvastatin (A) therapy in hyperlipidemic patients with cardiovascular diseases (CVD) and type 2 diabetes mellitus (DM) (OLYMP trial)

Bubnova M G , Aronov D M , Bubnoa Marina , Aronov David

Objective: Objective to study the hypolipidemic efficacy, hepatoprotective activity, and tolerance of the fixed-dose combination of essential phospholipids with methionine (EPL+M) - Eslidine in the combination therapy with A in patients (pts) with cardiovascular diseases (CVD) and type 2 DM who suffer from hyperlipidemia (HL) in order to optimize their treatment in daily clinical practice.Subjects and methods: The trial enrolled 60 pts (mean age 58.1&#17...
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ea0002sp4 | Society for Endocrinology Jubilee Medal Lecture | SFE2001

Recent studies in normal and abnormal growth hormone secretion

Besser G

The nature of the hypothalamic factors which control GH secretion in animals and man have emerged since the description of somatostatin (SS) in the early 1970s. Confusion originally arose when the ubiquitous distribution and apparent non-specificity of the actions of SS were established. Understanding of the paracrine nature of SS's action and the dependence of the specificity of its effects upon the locus of secretion and its short half-life in the circulation provided for an...
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ea0007p19 | Comparative endocrinology | BES2004

Changes in bone mineral density in response to growth hormone replacement in adults with isolated growth hormone deficiency compared with multiple pituitary hormone deficiencies

Waterhouse M , Loureiro R , Walker D , Besser G , Monson J

The contribution of conventional hormone replacement to the clinical features attributed to adult growth hormone deficiency (GHD) is poorly defined. We measured baseline bone mineral density (BMD/DXA) at the lumbar spine and femoral neck in patients with isolated GHD (IGHD, 16 patients, 14 female, 4 childhood onset, mean age 39, range 19- 63 years) and patients with multiple pituitary hormone deficiencies (MPD, 135 patients, 94 female, 14 childhood onset, mean age 44, range 19...
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ea0005p91 | Diabetes, Metabolism and Cardiovascular | BES2003

Baseline clinical characteristics and response to growth hormone replacement therapy in adults with isolated growth hormone deficiency in comparison with multiple pituitary hormone deficiencies

Waterhouse M , Loureiro R , Walker D , Besser G , Monson J

The contribution to adult growth hormone deficiency (GHD) of hormone replacement and other aspects of hypopituitarism are poorly defined. We compared baseline characteristics and response to GH treatment of patients with isolated GHD (IGHD, 16 patients) to patients with multiple pituitary hormone deficiencies (MPD, 135 patients). At baseline, MPD patients showed significantly greater waist-hip ratios (0.87 plus/minus 0.007 vs. 0.82 plus/minus 0.02, mean plus/minus SD; P < 0...
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ea0066d1.1 | (1) | BSPED2019

Besser Rachel

Dr Rachel Besser BSc MBBS (Hons) MRCPCH PhD, is a consultant in paediatric endocrinology at Oxford Children’s Hospital, and Honorary senior clinical lecturer at the University of Oxford, working with both the NIHR Oxford Biomedical Research Centre and the Wellcome Centre for Human Genetics. She came to Oxford in 2016 and was Clinical Lead between 2016–2018, and is now Research and Audit lead for the department. Rachel splits her job between clinical diabetes and diab...
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ea0029oc4.4 | Pituitary Basic | ICEECE2012

Identification of coupling specificity between somatostatin receptor 5 (SST5) and G proteins by a bioluminescence resonance energy transfer (BRET) technique: the role of GoA protein

Peverelli E. , Mantovani G. , Vitali E. , Busnelli M. , Chini B. , Lania A. , Beck-Peccoz P. , Spada A.

In this study we employed a novel bioluminescence resonance energy transfer (BRET) biosensor to study the coupling specificity of somatostatin receptor 5 (SST5) and its naturally occurring mutant R240W in living cells. Our previous data demonstrated that SST5 carrying the R240W mutation as well as other mutations in the third intracellular loop maintained the ability to inhibit intracellular cAMP levels similarly to the wild-type but failed to mediate the inhibition of intrace...
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ea0036cme6 | CME Session | BSPED2014

Trainees update

Besser Rachel , Steele Caroline

The trainee reps (Drs C Steele and R Besser) will provide an update on their activities on behalf of the trainees in the past year including:i) Update of the trainees’ section of the BSPED website.ii) Results of a recent survey of GRID trainees aimed to track training and for future workforce planning.iii) Ongoing activities (such as trainees’ section of the BSPED newsletter) and number of e-mail co...
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ea0007p93 | Endocrine tumours and neoplasia | BES2004

A new operation for adrenal pathology: laparoscopically-assisted mini-adrenalectomy

Abdel-Rahamn A , Laban C , Besser G , Monson J , Grossman A , Savage M , Jenkins P , Drake W , Chew S , Ashby M , Carpenter R

Background: Standard trans-peritoneal adrenalectomy has disadvantages, which are minimised by a less invasive procedure, but laparoscopic adrenalectomy is time consuming and unsuitable for large or malignant tumours.Aims: To evaluate our experience of all laparoscopically assisted mini-adrenalectomy using a subcostal incision 10 cm or less, since July 1999.Methods: Data were collected on wound size, operative time, blood loss (fall...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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