Endocrine Abstracts

Introduction: The total energy expenditure in pregnancy is increased largely due to elevated basal metabolic rate (BMR) during pregnancy. The aim of this study is to evaluate the effects of gestational diabetes on basal metabolic rate, body weight and HbAlc, by comparing these parameters in gestational diabetic and healthy pregnant women.Method: Fifty-eight gestational diabetic women (GDM) and fourty healthy non diabetic pregnants who had normal thyroid ...

Objective: Stress has been linked to several diseases. In the course of stress; blood sugar. cortisol and catecholamine levels increase. Visceral hypersensitivity will increase due to catecholaminergic discharges leading to an over-induction of the intrapancreatic secretion. A chronically stress has a role in the induction of insulin resistance in different tissues and pancreas begins to release excessive insulin causing burned out pancreas. For this reason, it becomes insulin...

Plant growth factors are used commonly in agriculture. The effect of these factors on human health is unknown. Gibberellins are the most commonly used growth factors that have the structure of Diterpenoid acid. One of the gibberellins (GA3) induces tumor formation in mice but the mechanism of action is not known. We here examined changes in levels of GH and IGF-1 and examined whether there is a correlation between growth factors’ levels and weight changes.<p class="ab...

Adrenal lymphangioma is a rare benign tumors of the adrenal gland. Because of the increased use of imaging methods in recent times, the diagnosis is usually made incidentally. It is usually due to malformation between the lymphatic and the venous system. Those with small indiameters are generally asymptomatic and can be evacuated by needlea spiration. However, surgery is recommended for cysts over 6 cm in diameter due to risk of infection, bleeding, compression of neighboring ...

Aim: The incidence of nodular thyroid disease is high among patients with insulin resistance. The aim of this study is to evaluate the relationship between BRAFV600E mutation and insulin resistance in the patients with papillary thyroid cancer.Materials and methods: We examined clinical and laboratory data of 103 patients who had been followed up by our department between the years 2010 and 2015. The diagnosis of insulin resistance (IR) was made when the...

Anaplastic thyroid carcinoma (ATC) is one of the most aggressive and lethal human malignancies. The median survival time following diagnosis is typically six months or less. Rapidly growing tumors may cause respiratory failure by compressing trachea. A 71-year-old woman presented with 1-month history of dyspnea, cyanosis and rapidly enlarging neck mass for the past 2 weeks. She had been suffering from multinodular goiter disease. Physical examination revealed a large, fixed an...

Aim: It is well known that there is a strong relationship between chronic inflammation and tumorigenic process. The cytological diagnosis of follicular neoplasm (FN) carries a 20–30% risk of malignancy for thyroid nodules. In this study, we aimed to evaluate whether preoperative neutrophil to lymphocyte ratio (NLR) is a predictive factor for malignancy in thyroid nodules diagnosed as FN on cytology.Materials and methods: A total of 139 patients with...

Primary hyperparathyroidism in the most common cause of hypercalcemia. 87% of the cases present with single adenoma, 9% of them have hyperplasia, while multiple adenomas and parathyroid malignancy are detected in 3 and 1% of the cases, respectively. Although it is rare, parathyroid adenomas may be ectopic. The most common locations for ectopic parathyroid adenomas are thymus, tracheaesophageal cleft, carotis sheet, intrathyroidal and paraesophageal area. In this study, we aime...

Aim: There are some studies suggesting that the risk of developing cancers,especially thyroid cancer, is increased in the patients with acromegaly. The prevalence of thyroid cancer is 1.2-10.6% among the patients with acromegaly. In this study, we aimed to evaluate clinical and histopathologic characteristics of thyroid cancer among the patients with acromegaly.Method: We retrospectively evaluated the patients with acromegaly who had been followed-up by ...

Hyalinizing trabecular tumor is an uncommon, controversial lesion of thyroid gland. Hyalinizing trabecular neoplasm share similarities with medullary thyroid carcinomas (MTC) and exhibit nuclear features resembling papillary thyroid carcinoma (PTC). However, the clinical behaviour unclear. We aimed to present a rare case of hyalinizing trabecular tumor of thyroid gland and ten-year follow up. A 54-year-old woman who was being followed up because of multinodular goiter on exami...