Endocrine Abstracts

IntroductionClinical guidelines for the prevention and treatment of vitamin D deficiency in adults were formulated and implemented into clinical practice by the Russian association of endocrinologists in 2014. While having multiple health benefits, in some cases, prescribing vitamin D supplements may be accompanied by its toxicity, which has various manifestations and exert potentially dangerous health consequences.Aim<p class=...

Introduction: Primary adrenal lymphoma is rare, representing less than 1% of non-Hodgkin lymphomas.1 The clinical presentation is non-specific, symptoms of adrenal insufficiency may occur with bilateral lesions, and work up can be tricky.2Background: A 60-year-old man was admitted mid-January 2020 for acute left abdominal pain. He had no medical history and didn’t smoke or take any medication. He had no history of recent trauma...

A 37-year-old Caucasian female, pharmacist, referred to Diabetological center in February 2017. The main complaint was frequent urination.Medical history: She was diagnosed with T2DM at the age of 32 year. She was taking Metformin 850 mg twice daily. Her plasma glucose was 7.8 mmol/l at fasting; 10.8 mmol/l postprandial.Family history: Her father has elevated glucose levels also (up to 8 mmol/l before meal). Her moth...

A 40-year Caucasian female referred to Diabetes centre in November 2016. Her main complaints were 20 kg weight gain over the past 4 years, muscle weakness, high blood glucose readings, high blood pressure (up to 180/100 mmHg),menstrual irregularity.Medical historyShe was diagnosed with T2DM at the age of 39 year. She did not take any blood glucose lowering medication. Her blood glucose readings were: 12 mmol/l at fasting, 20 mmol/l...

Objective: To evaluate the diagnostic accuracy of thyroid ultrasound characteristics of nodules in prediction of malignancy.Material and methods: Retrospectively were analyzed 102 patients who underwent for FNA biopsy of thyroid nodule. All patients were examined by one ultrasound examiner. Size, taller than wide, echogenicity, borders, halo, calcification, and internal vascularity were recorded in all examined nodules. The Bethesda System for Reporting ...

Obesity and diabetes mellitus type 2 are proinflammatory states associated with increased disease severity in rheumatoid arthritis (RA). Weight loss is associated with improved disease activity in rheumatoid arthritis (RA). Furthermore science experiments demonstrated weight-independent anti-inflammatory and immunomodulatory effects of GLP-1 receptor agonists. Moreover, in vitro studies found anti-inflammatory effects of GLP-1 receptor agonists in fibroblast-like syno...

Nowadays fat tissue is considered as endocrine organ responsible for metabolism of sex hormones. Obesity is accompanied by a decrease in biosynthesis of 17β-estradiol (2-hydroxyestrone) inactive metabolites and increased production of aggressive metabolites (16-hydroxyestrone). This factor leads to hyperproliferative syndrome, which includes hormonal-dependent lesions of target organs: uterine leiomyomas, adenomyosis, hyperplasia of endometrium, tumor-like lesions of the ...

Vologda is situated in the North-Western region of Russian Federation. It is mostly rural – about 30% of population lives in remoted villages. One can compare Vologdàs region with Greece – same amount of land area (approximately 140000 m2), but the population density is 10 times less (8 per km2 and 85 per km2 respectively). The Vologdàs region population is approximately 1151000, the amount of Diabetes patients is 42 000 (3,7% of overall population). The te...

Dehydroepiandrosterone sulfate (DHEAS) is a sulfated ester of dehydroepiandrosterone. Studies of large number of males with DHEAS pathology are infrequent.Objective: To perform an investigation of significance of DHEAS assessment in males of different ages.Subjects. Methods. ResultsWe analyzed clinical data of 3533 patient’s (3013 females and 520 males) from DHEAS assessment lists of Vilnius and Kaunas ...

Aim: Of the study was to establish normal penile size and testicular volume in healthy Lithuanian newborns.Methods: Of 1204 newborn boys were examined in Panevėžys Hospital due to genitometry. Those with cryptorchidism or hypospadias were excluded. Penis size was measured in 1042 and testicular volume in 712 healthy newborns. The stretched penile length was measured between the pubic ramus and the tip of the glans and the diameter – in...