Endocrine Abstracts

Objective: To investigate gender differences in spatial orientation and verbal memory we conducted a study in 21 healthy young women and men (eleven women). Participating women were required to be in the mid-luteal phase of the cycle. Hormone profiling for behavioural studies is often performed in saliva samples to avoid venous blood sampling. We have compared simultaneously collected blood and saliva samples to confirm the presence of the luteal phase.M...

Diabetes is a chronic condition that predisposes to a wide range of foot problems that potentially end with ulcer formation. The purpose of this manuscript is to report 68 participants’ diabetic foot problems self-treated with complementary therapies. Participants were recruited from nine healthcare facilities in Jordan and interviewed via survey. Their responses to an individual question seeking information about complementary therapy usage was analysed using content ana...

Purpose: To examine the prevalence and awareness of metabolic syndrome (MetS) in high-risk individuals attending 30 internal medicine clinics in Amman, Jordan, and also to evaluate the various factors associated with increased risk of MetS among them.Methods: This retrospective cross-sectional study was carried out across Amman, Jordan from October to December 2014. During the study period, 900 high-risk individuals (with hypertension, diabetes, central ...

Diabetes mellitus (DM) is a disease of epidemic proportions. Most of DM patients are classified as type 2 diabetes mellitus (T2DM) that is linked with resistance to insulin action on target tissues. In 2015, 415 million people were living with DM worldwide with the highest prevalence rates recorded in the Oceania and the Middle East and North Africa (MENA) regions. In Jordan, a MENA country, the prevalence of DM has increased from 13% to 17% over a 10-year period (1994–20...

Diabetes is a major health problem that affects 8.5% of adults worldwide, and 13.2% of adults in Jordan. Studies suggest a bidirectional relationship between diabetes and chronic depression. Diabetic patients are twice as likely to suffer from depression that is symptomatically worse when compared to nondiabetic individuals. Depressed diabetics suffer from poor glycemic control and increased risk of diabetes complications. Because little is known about the bidirectional relati...

Aim: To assess the impact of age, sex, duration of diabetes and body mass index confounders on diabetes control in a Jordanian cohort of T2DM at endocrine clinic at KHMC.Patients and methods: Patients randomly selected over 18 months from outpatient clinic at KHMC in Amman-Jordan. Diabetes control assessed by mean of latest 3 HbA1c and FBS. Patients were divided in 2 groups according to age (<55 years vs >55 years), gender, duration (<10 year...

Background: The worldwide type 2 diabetes mellitus (T2DM) prevalence is increasing dramatically. Inflammation is involved in the pathogenesis of T2DM and development of insulin resistance. Lack of diabetic control is associated with alteration in the endocrine milieu and various health sequalae’s. The aim of this research was to assess if uncontrolled T2DM is associated with increased serum levels of inflammatory cytokines and growth factors when compared with controlled ...

Case History: A 26 year old female patient was referred to her local endocrine clinic having presented to her GP complaining of ankle swelling. Routine biochemistry revealed a suppressed TSH (<0.05 U/l), and reduced serum levels of free T4 (2.0 pmol/l) and T3 (3.2 pmol/l). Random serum cortisol measurements were also elevated on 2 separate occasions (1266 nmol/l and 991 nmol/l). Clinical examination revealed her to be clinically euthyroid with no evidence of ...

Case History: A 26 year old female patient was referred to her local endocrine clinic having presented to her GP complaining of ankle swelling. Routine biochemistry revealed a suppressed TSH (<0.05 U/l), and reduced serum levels of free T4 (2.0 pmol/l) and T3 (3.2 pmol/l). Random serum cortisol measurements were also elevated on 2 separate occasions (1266 nmol/l and 991 nmol/l). Clinical examination revealed her to be clinically euthyroid with no evidence of ...

Introduction: Cushing’s Syndrome is caused by elevated levels of cortisol and is characterized by dozens of non-specific physical, metabolic, and neuropsychological symptoms. The extent of damage a patient will face is directly related to time to diagnosis, experience of the doctors and surgeon, and the support and education they receive after surgery. The spectrum of long-term needs faced by patients who have been exposed to prolonged elevated cortisol are not well repre...