Endocrine Abstracts

Introduction: Pregnancy in hypopituitary women is a rare and poorly studied clinical condition. Management difficulties and obstetrical complications have been associated with this condition.Objectives: To define the characteristics, follow-up and perinatal outcomes in hypopituitary pregnant women attended at our centre.Methods: The clinical data of the hypopituitary pregnant women (deficiency of two or more pituitary hormones), an...

Introduction: Non-classical congenital adrenal hyperplasia (NCCAH) due to 21-hydroxylase deficiency is one of the most frequent autosomal recessive diseases. Genetic analysis performed for genetic counselling revealed a miscorrelation with the clinical diagnosis in several patients at our centre.Aim: Confirm the genetic diagnosis of NCCAH in women attended for this condition.Materials and methods: Consecutive patients attended at o...

Hyperfunctional nodules of the thyroid are rarely associated with thyroid cancer, for these reason are rarely biopsied. Although multiple theories have being proposed, the relationship is still uncertain. After performing a MEDLINE literature search, we found in multiple retrospectives analysis, that patients with hyperthyroidism with hyperfunctional nodules have an estimated of 0.3–16.3% prevalence of malignancy. In our study forty-eight hyperthyroid cases were prospecti...

Introduction: Obstructive sleep apnea-hypopnea syndrome (OSAHS) and obesity are two pathologies increasingly prevalent in population related to each other. Obesity is present in between 60-90% of patients diagnosed with OSAHS being the most important modifiable risk factor. Obesity influences the risk factor for OSAHS degree of severity, increasing its severity by up to 30%. The degree of relation between both pathologies, we created a protocol Endocrinology and Pneumology ser...

Primary hyperparathyroidism (PHPT) is a common condition. The prevalence since the introduction of multichannel analysers is approximately 1:1000, with the older female being the typical patient. PHPT is predominantly a sporadic disorder. Surgery remains the only curative approach to most primary hyperparathyroidism (PHPT), medical treatment with cinacalcet has been proven to be an alternative for patients with hyperparathyroidism.Objective: Analyze trea...

Introduction: Low testosterone serum levels are associated with increased mortality in non-diabetic males. However, knowledge about the association between male hypogonadism and mortality among type 2 diabetic (T2DM) men is limited due to short follow-up periods in the few existing studies.Objective: To assess the association between hypogonadism and mortality in diabetic men.Material and methods: 263 unselected men with T2DM (mean...

Background: Hypothyroidism is one of the most frequent conditions in endocrinology. Despite of that fact, indications for treatment differ among specialists in Spain.Aims: To identify attitudes of Spanish endocrinologists in the use of levothyroxine (LT4) therapy and the management of hypothyroidism.Methods: The members of the Sociedad Española de Endocrinología y Nutrición (Spanish Society of Endocrinology ...

Introduction: Doege-Potter syndrome (DPS) is a rare paraneoplastic syndrome consistent in non-islet-cell tumor hypoglycemia associated with solitary fibrous tumor (SFT). Pathogenesis of hypoglycemia has been attributed to the production of insulin-like growth-factor-2 (IGF-2) by tumor cells. We report two DPS patients with metastatic extrapleural SFT.Case 1: A 42-year-old man with SFT of the mesocolon that had been operated in 2010, presented with metast...

Objectives: The use of thyroid hormones (TH) to treat obesity is not supported by evidence based on efficacy and safety, and this is reflected in recommendations of major international guidelines on hypothyroidism and obesity. We aimed to explore views about this practice among European thyroid specialists and their associations with respondent characteristics.Methods: Thyroid specialists from 28 countries were invited to participate in a questionnaire s...

Objectives: To study blood pressure circadian pattern in patients with impaired fasting glucose (IFG) evaluated with ambulatory blood pressure monitoring (ABPM).Methods: Cross-sectional study evaluating patients taken from the Spanish ABPM Registry. Normoglycemia was defined as glucose <100 mg/dl and IFG as glucose 100–125 mg/dl. All patients underwent 24-h ABPM with a Spacelabs ambulatory blood pressure system. ABPM was performed according to s...