Endocrine Abstracts

Background: Neuroendocrine tumours of the appendix (ANET) are relatively indolent tumours typically identified incidentally at surgery for suspected appendicitis. The role of right hemicolectomy (RH) for tumours with ‘high risk’ features is debated. We compared the management of ANET at three centres against ENETS criteria for therapy selection.Methods: Retrospective review of all patients diagnosed with ANET at three tertiary centres. Patients...

Background: Many patients require IV insulin during their critical illness. Maintenance of insulin in St James’s Hospital ICU is governed by a local protocol. At the time of ICU discharge, IV insulin therapy is often stopped. Transitioning from IV to subcutaneous insulin is often done with endocrinology input. If this is unavailable inappropriate insulin dosing may increase the risk of hypo-/hyperglycaemia.Aims: To reduce the number of episodes of h...

James A Fagin, Memorial Sloan-Kettering Cancer Center, New York, USA. AbstractJames A. Fagin is Chief of the Endocrine Service and a Member of the Human Oncology and Pathogenesis Program at Memorial Sloan-Kettering Cancer Center in New York, and a Professor of Medicine at Weill Medical College of Cornell University. He was formerly the James Heady Professor of Medicine and Director of the Division of Endocrinology and...

Clinical Case: A 51 year old woman of south Asian descent was referred by her GP to outpatient endocrine clinic for assistance with her mixed hyperlipidaemia (Cholesterol 9.5 mmol/L, HDL Cholesterol 1.03 mmol/L Triglycerides 6.7 mmol/L). Her past medical history included a previous hemithyroidectomy for removal of a thyroid nodule (histologically benign) and obesity.The patient’s symptoms were of weight gain (5 kg in 18 months...

Clinical Case: A 51 year old woman of south Asian descent was referred by her GP to outpatient endocrine clinic for assistance with her mixed hyperlipidaemia (Cholesterol 9.5 mmol/L, HDL Cholesterol 1.03 mmol/L Triglycerides 6.7 mmol/L). Her past medical history included a previous hemithyroidectomy for removal of a thyroid nodule (histologically benign) and obesity.The patient’s symptoms were of weight gain (5 kg in 18 months...

You don’t have to be a digital native to use technology effectively in teaching. Even self-confessed technophobes can make meaningful improvements in their use of digital learning with only a little bit of guidance and support. Technology is a ubiquitous feature of higher education, which has been consolidated during the COVID-19 pandemic. However, with so many options on the market it can be incapacitating to try and choose. This is further complicated by local institut...

Case History: A 26 year old female underwent Roux-en-Y gastric bypass (RYGB) surgery for intractable peptic ulcer disease on a background of obesity. She had a history of 40kg weight gain over 8 years (weight 123 kg, BMI 41.1 kg/m2), hypertension, depression, insomnia and newly diagnosed type 2 diabetes. Following surgery, weight loss was disappointing (nadir 112 kg, −11 kg, −8.9%TBW, −22.9%EBW, BMI 37.5 kg/m2) and diabetes and hypertens...

Lawyers need doctors. When the work of the legal profession leads into areas of clinical medicine it is important that expert clinicians are there to explain and advise on the clinical issues. A good clinician can give valuable advice to the parties involved, and can also assist the courts in reaching a just and equitable conclusion.In endocrinology an expert is most commonly asked to advise in matters relating to an allegation of clinical negligence. So...

Lawyers need doctors. When the work of the legal profession leads into areas of clinical medicine it is important that expert clinicians are there to explain and advise on the clinical issues. A good clinician can give valuable advice to the parties involved, and can also assist the courts in reaching a just and equitable conclusion.In endocrinology an expert is most commonly asked to advise in matters relating to an allegation of clinical negligence. So...

The use of RAI for remnant ablation, as adjuvant therapy or as treatment for recurrent or metastatic disease is undergoing a significant reappraisal, based on its questionable efficacy in various disease contexts. Until recently postoperative RAI treatment was given to all patients with thyroid cancer regardless of the pathological stage of the disease. Although its use for low risk forms of thyroid cancer has diminished, current indications for adjuvant RAI treatment are not ...