Endocrine Abstracts

BackgroundDiabetic retinopathy is the leading cause of blindness in working-age adults in developed world. Derangements of ubiquitine-proteasome system and telomere length have been associated with microangiopathy in diabetes. Until now, limited data are available on above markers in diabetic retinopathy in type 1 diabetes (T1D).AimThe aim of this work was to compare serum proteasome concentration and telomer...

Aim: to assess sleep quality in patients with type 2 diabetes (T2D) experiencing low perceived psychological stress and high perceived psychological stress.Methods: Perceived stress level and sleep quality were assessed in 154 patients with T2D (58 men, 96 women, age 58.7±11.8 years), using Perceived Stress Scale (a higher score denotes a higher level of perceived stress) and Pittsburgh Sleep Quality Index (a higher score denotes worse sleep quality)....

Case: A 34-year-old, Saudi male, known case of hypothyroidism with coarse (potato) voice, referred for isotopic thyroid scan. After withdrawing the Eltroxin for one month, thyroid scan was done and showed abnormal uptake rounded in shape and appears bi-lobar, seen highly in the neck, at the midline, between both submandibular glands. No evidence of any uptake at the normal anatomical position of the thyroid gland. Ultrasound of the neck was done and showed large submental mass...

Background: Obesity exacerbates many aspects of the PCOS phenotype, especially cardiovascular risk factors, infertility. The objective of the study was to determine the effects of overweight and obesity on the metabolic features of PCOS.Material and methods: 116 PCOS women (according to Rotterdam criteria, mean age 27.16±3.87 years) were investigated in Vilnius city (Lithuania) in 2009–2011. Height, body mass and waist circumference were measur...

Background: The objective of the study was to compare distributions of subcutaneous adipose tissue and metabolic parameters in lean women with PCOS and lean healthy women.Materials and methods: PCOS women (according to Rotterdam criteria, mean age 26.54±3.65 years) and 70 healthy control women (mean age 27.84±3.63 years) were investigated in Vilnius city (Lithuania) in 2009–2011. A skinfold caliper device was used to measure skinfolds thic...

Diabetes mellitus type 2 (DM2) is affecting physical and psychological health.Objective: Compare anthropometric data, body composition, lipids levels, emotional state, quality of life (QoL) of DM2 patients and that of healthy persons of the same age.39 persons (58.1±9.6 years) with DM2 (18 male, 21 female) and 41 healthy persons (54.3±9.9 years) (22 male, 19 female). Profile of Mood State (POMS) used for emotional state e...

Background: It is well recognised that the most frequent cause of mineralocorticoid induced hypertension is primary hyperaldosteronism. Excess 11-deoxycorticosterone (11-DOC), which is a precursor molecule for the production of aldosterone, may in rare cases be the cause of the mineralocorticoid induced hypertension in patients with normal or low aldosterone levels.Case: We describe a 70 year old female patient with a background of treated breast cancer ...

Adult patients with acromegaly after pituitary adenomas usually have emotional problems, impaired quality of life. Objective was to detect possible differences of emotional state between patients with acromegaly after pituitary adenomas and healthy age- and sex-matched controls and to outline possible gender-specific differences.Patients and methods: 12 males (age 49.6±10.2 years) and 29 females (age 51.5±9.5 years) with acromegaly after pituit...

Introduction: Diabetic nephropathy (DN) is a severe complication of type 1 diabetes mellitus (T1DM) and has become common primary disease leading to end-stage renal disease worldwide. Abnormalities in lipid metabolism is very important in the progression of renal damage in patients with T1DM.Aim: to assess the relationship between lipid abnormalities and diabetic nephropathy in type 1 diabetes mellitus patients. Methods: we perform...

Introduction and aim: Turner Syndrome (TS) is associated with a variety of morbidities affecting nearly every body system, and necessitates multidisciplinary management. To facilitate care, the International Turner Syndrome Consensus Group have drafted Clinical Practice Guidelines that were disseminated to ESE members in April 2017. The aim of this audit was to assess whether current management of adolescent and adult TS women in our care is in accordance wi...