Endocrine Abstracts

Introduction and objectives: The most important risk factors of chronic kidney disease (CKD) are diabetes and hypertension. In addition, obesity and metabolic syndrome (MetS) are independent predictive factors of CKD. The objective of our study was to investigate if MetS affects renal function of patients who underwent partial nephrectomy for localized renal cell carcinoma (RCC).Patients and methods: 50 cases of T1N0M0 RCC patients who underwent partial ...

Introduction: Diabetes mellitus is a major public health problem affecting all ages worldwide. In Tunisia, 18% of the population has diabetes mellitus. In fact, it is one of the first ten causes of death in our country.Therefore, self-management education for diabetic patients play an important role in reducing diabetes complications and mortality rate. The education is conducted not only by doctors, but also by nurses.Purpose: The aim of this study is t...

Introduction: Gestational diabetes mellitus (GDM) is a common and increasing complication, concerning 2–17% of pregnancies [1]. This glucose intolerance often resolves after delivery, and rarely becomes permanent type 2 diabetes, exceptionally type 1 diabetes (T1D). We present a case of a patient with GDM, which unexpectedly revealed T1D. Case report: A 33-year-old woman consulted for GDM. Her family medical history includes hypothyroidism in her ma...

Introduction: Type 1 diabetes (T1D) is a progressive autoimmune disease, the diagnosis is obvious in classic forms. However, misleading forms are possible, sometimes leading to inappropriate treatment. We report the case of two type 1 diabetic patients who were treated for years with oral hypoglycemic drugs.Case report: Patient 1: Mr. M, aged 34, with a family medical history of type 2 diabetes (T2D), was diagnosed with diabetes revealed by a polyurea-po...

Introduction: Growth hormone deficiency (GHD) is a rare cause of delay of growth. However, it is primordial to screen for it since its presence leads to a specific treatment which improves statural prognosis. GHD should be confirmed through stimulation tests such as Insulin Tolerance test (ITT) or Clonidine Stimulation Test (CST). The objective of our study was to compare these two diagnostic tools.Methods: We conducted a retrospective study in the endoc...

Non-secreting pituitary adenomas (NSPA) are relatively rare benign tumors their prognosis depends essentially on their endocrine and ophthalmological repercussions the aim of our study is to outline their clinical, biological, radiological aspects, and the therapeutic choice.Methods: Retrospective study of 17 patients with non secreting pituitary adenomas.Results: We identified 17 patients with NSPA split into 12 women and 5 men wi...

Introduction: Metastatic or locally advanced prostate cancer is treated with surgical or medical hormone therapy. Preservation of the patient’s quality of life is a major parameter that influences the management at this stage. Comparative studies between both types of hormone therapy that consider the patient’s quality of life are almost nonexistent. The objective of our study is to evaluate the impact of medical and surgical castration on the quality of life in pati...

Introduction: Hashimoto’s encephalopathy or SREAT (steroid-responsive encephalopathy associated with auto-immune thyroiditis) is a rare autoimmune disorder that is particularly corticosensitive and whose pathogenesis remains poorly understood. It is associated with high levels of antithyroid antibodies in plasma and/or CSF. Clinical manifestations are deceptive and may include cognitive and behavioral disturbances, seizures or abnormal movements.Cas...

Introduction: The majority of systemic diseases result from an autoimmune process. Primary adrenal insufficiency (Addisson’s disease AD) is also frequently caused by an autoimmune process. Their association is rare but can be seen in the framework of autoimmune polyendocrinopathies. We report 2 observations associating an autoimmune adrenal insufficiency with a systemic disease.Observation 1: We describe the case of a 50-year-old patient initially a...

Introduction: The use of GH treatment in patients with macroadenomas and GH deficiency is of concern to the clinician due to the theoretical stimulation of tumor regrowth by GH substitution. We report the case of an 18-year-old adolescent with a macroprolactinoma causing delayed stature and puberty.Observation : We report the case of an 18-year-oldadolescent who consulted for gynecomastia with delayed stature and puberty. Physical examination displayed a...