Endocrine Abstracts

Background: ACTH-dependent Cushing’s syndrome (CS) is mostly associated with corticotroph adenomas or, infrequently, ectopic ACTH secretion(EAS). Adrenals may show diffuse bilateral enlargement or even macronodules. Adrenal metastases may occur in various cancers. They are often bilateral, irregular, with attenuation values >20 Hounsfield units(HU) on unenhanced CT scan and elevated SUVmax on FDG-PET scan. They may cause adrenal insufficiency due to the destruction of...

Background and aim: Revelation of the incidence of CH is of great value at the background of iodine deficiency (ID) existing in Georgia. Screening on CH in our company with consequent monitoring of the newborns with neonatal hyperthyreotropinemia (NHT) started in September 2010.Materials and methods: During the first year period 70 731 newborns from all over Georgia underwent TSH (mU/l) determination from blood spots, taken at 24–72 h after birth an...

Background and aims: Cardiovascular disease (CVD) is a leading causes of death in type 2 diabetes mellitus (T2DM), thus prevention of CVD is of utmost importance. Our aim was to determine whether the ESC/EASD guidelines on CVD prevention in T2DM patients are followed in clinical practice in Georgia.Materials and methods: In total, 824 T2DM patients (age <80 yrs) with no history of coronary or other atherosclerotic disease, who entered Georgian Diabet...

Background and Aim: One of the greatest problem in pregnancy, complicated by diabetes is screening and appropriate care for women, whose diabetes is manifested during pregnancy. The study is aimed at gathering epidemiological data on gestational diabetes mellitus (GDM) and evaluating the of appropriate therapy in this condition.Materials and Methods: Screening for GDM was carried out in – 692 pregnant women. GDM was observed in 3.3% (22 women) and i...

Background: The COVID-19 pandemic changed to the daily life of individuals. These included lockdown and social distancing During COVID-19 pandemic. Healthcare providers from different institutions had to adapt to the way of supporting and managing patients with different chronic conditions including diabetes. The implementation of lockdown affected diabetes care. COVID-19 pandemic enabled healthcare professionals to apply innovation including social networks/telemedicine/telep...

Background: Diabetic neuropathy is the most prevalent chronic complications of diabetes. This heterogeneous group of conditions affects different parts of the nervous system and presents with diverse clinical manifestations. Diabetic peripheral neuropathy (DPN) is one of the common complication of type 2 diabetes and can lead to foot ulcer, gangrene or amputation. The risk of developing diabetic neuropathy increases with age, diabetes duration and poor control of blood glucose...

IntroductionRecently, apart from its main physiologic role, the active form of vitamin D has also been recognised to have anti-inflammatory and immune-modulating properties. Accumulating evidence suggests that Vitamin D deficiency is associated with increased prevalence of various autoimmune diseases, and in particular, with autoimmune thyroid disease. Despite contradicting evidence, the balance is tipping towards inverse correlation between vitamin D de...

Introduction: Hyponatremia from SIADH secondary to undiagnosed Myelomas are extremely rare and we present one such case.Clinical case: 63 year old woman with background of MGUS under regular haematology review/ILD/NAFLD/IHD presented with severe constipation on top of weakness, weight loss and tingling in the peripheral extremities. She was euvolemic on admission with Serum Sodium 124mmol/l, Potassium 4.3 mmol/l, Urea 3....

Introduction: The incidence of thyroid cancer in women, especially in reproductive age seems to be significantly increasing in Georgia and generally, worldwide. Thyroid cancer is the third most common cancer after breast cancer and uterine cervical cancer, among women aged 25 to 45 years. Multiple epidemiological studies have shown, that the prevalence of thyroid cancer is higher in women in the reproductive age (18-49), which could be explained by reproductive and menstrual f...

Objective: Post Covid Syndrom (PCS) after Covid Pamdemic is a major couse of morbidity for Diabetic patients. In the last 30 years, a new metabolic risk factor for vascular damage – hyperhomocysteinemia (HtHcy) has been identified and is considered as an independent risk factor for the development of cardiovascular pathologies and the possible lethal outcome.Aim of study: This study was undertaken to check association of plasma Hcy level in post cov...