Searchable abstracts of presentations at key conferences in endocrinology

ea0041gp233 | Thyroid Cancer (1) | ECE2016

Malignancy risk and false negative rate of fine needle aspiration cytology in thyroid nodules equal or greater than 4 cm

Bestepe Nagihan , Ozdemir Didem , Ali Tam Abbas , Dellal Fatma Dilek , Kilicarslan Aydan , Parlak Omer , Ersoy Reyhan , Cakir Bekir

Background: We aimed to evaluate malignancy rate in thyroid nodules ≥4 cm and determine false negativity of fine needle aspiration biopsy (FNAB) in these nodules.Methods: Patients who underwent thyroidectomy between January 2007 and December 2014 in our institution were reviewed. Demographical and clinical data and preoperative ultrasonography (US) findings were obtained from the medical records. The nodules in these patients were grouped as &#8805...

ea0090ep552 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Multiple fingers with multiple endocrine disorders

Elawad Omer

Background: Bardet–Biedl syndrome is a rare multisystem autosomal recessive disorder that falls under the spectrum of ciliopathy disorders. This ciliopathy is characterized by rod–cone dystrophy, renal malformations, polydactyly, learning difficulties, central obesity, and hypogonadism [1]. It was first described by Bardet [2] in 1920 and then by Biedl [3] in 1922. Its prevalence in Europe and North America is 1:100 000 [4]. The incidence o...

ea0070ep533 | Hot topics (including COVID-19) | ECE2020

The renin–angiotensin system blockers and the risk of COVID-19

Omer Tahir

Introduction: The year 2020 has witnessed a new global pandemic caused by an encased single-stranded RNA virus identified as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The exceptionally infectious capability of the virus, along with case fatality rate ranging from 0.99% to above 3%, have raised major global concerns.COVID19 and Risk factorsEvidence from several observational studies suggests risk factors for ...

ea0073aep329 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

The role of obesity management in the reversal of type 2 diabetes mellitus

Omer Tahir

The prevalence of Type 2 Diabetes Mellitus (T2DM) is drastically rising globally. It is projected to rise to close to 600 million in 2 decades. This rise parallels the increased prevalence of obesity which is estimated to rise to over 1 billion obese individuals by the year 2025. The association between the Body Mass Index (BMI) and type 2 Diabetes is well recognised. Raised BMI is a major predictor of the risk of T2DM. T2DM is associated with multiple complications and it wie...

ea0081ep931 | Reproductive and Developmental Endocrinology | ECE2022

Hyperprolactinaemia in postmenopausal women receiving long-term hormone replacement therapy: a case series

Omer Tahir , Adnan Adnan

Introduction: A few studies have examined the effect of Hormone replacement therapy (HRT) on serum Prolactin level (PRL) in postmenopausal women. It has been demonstrated that HRT can trigger a stimulatory response on PRL secretion. However, the significance of this is yet to be further evaluated given the great variation in PRL concentration during menopause which has not been fully meticulously examined.Case reports: We present 3 cases of postmenopausa...

ea0091wa2 | Workshop A: Disorders of the hypothalamus and pituitary | SFEEU2023

Giant prolactinoma requiring surgery

Omer Maria , Panicker Janki

35-year-old lady, has a background of Hypertension, oophorectomies for ovarian cancer and previous 2 IVF attempts, referred to endocrinology with three-week history of blurred vision, bitemporal hemianopia and large pituitary mass on MRI Upon assessment, she reported visual disturbance and intermittent headache. She has no periods which is expected with the history of oophorectomy, but she denied galactorrhoea or any symptoms suggestive of pituitary hormone excess or deficienc...

ea0091wd10 | Workshop D: Disorders of the adrenal gland | SFEEU2023

Adrenocortical carcinoma, a rare but aggressive tumour

Omer Maria , Hegde Pallavi

Case summary: A 40 year-old lady, who has a background of asthma, presented to emergency department with back pain radiated down to her left leg with associated foot drop. She also complained of 2 months history of weight gain, hirsutism, and menstrual disturbance. Clinical examination confirmed that she had some cushingoid features. Further assessment and investigations revealed that she had acute disc prolapse on MRI as well as an incidental finding of right adrenal gland an...

ea0091wf1 | Workshop F: Disorders of the parathyroid glands, calcium metabolism and bone | SFEEU2023

Hypercalcaemia in granulomatous disease

Omer Maria , Purewal Tejpal

Introduction: Hypercalcemia has been described in patients with granulomatous disorders. Most commonly sarcoidosis (10% of patients) and tuberculosis with three-fold increase in hypercalciuria. It’s due to production of calcidiol from calcitriol in the lung and lymph nodes that is independent of PTH. Main modalities of therapy are low-calcium diet, glucocorticoids, and treatment of the underlying disease.The Case: A 48-year-old male, referred to end...

ea0063ep144 | Thyroid | ECE2019

The rare association of graves disease with chronic spontaneous urticaria

Nasir Sadia , Omer Tahir

Background: Chronic spontaneous urticaria (CSU) is defined by the presence of recurrent urticaria (also called hives or wheals), angioedema, or both, for a period of six weeks or longer. CSU affects just 1% pf the general population and its etiopathogenesis is not well understood. CSU is known to be associated with various autoimmune conditions. However the association CSU and Graves Disease is very rarely seen in clinical practice.Clinical case: In this...

ea0056p630 | Clinical case reports - Pituitary/Adrenal | ECE2018

Low dose duloxetine and the risk of hyponatraemia

Omer Tahir , Seetho Ian

Duloxetine is a serotonin/norepinephrine reuptake inhibitor, prescribed frequently as a first line treatment for Diabetic neuropathy. It is also prescribed for treatment of depression, anxiety disorder and chronic musculoskeletal pain. Hyponatremia is a known adverse effect of most SSRIs including duloxetine and can potentially be life-threatening.Duloxetine induced hyponatremia, however, is relatively rare specially on low doses and is typically seen in the elderly frail pati...