Endocrine Abstracts

Introduction: The coexistence of thyroid nodules and autoimmune thyroid disease (ATD) has been widely reported. The aim of our study was to retrospectively evaluate the incidence of thyroid nodules associated with autoimmune thyroiditis. Sibiu county is a well known mild iodine deficiency area from Romania.Material and methods: We retrospectively analysed data from 600 patients (25–79 years) with autoimmune thyroiditis in University County Hospital ...

Background: South Asians have a higher prevalence of diabetes and increased complications compared to other ethnic minorities, leading to poorer health outcomes. There is a lack of evidence about knowledge of diabetes self-care behaviors amongst this group. Having such knowledge is crucial in preventing complications and providing effective health services.Objectives: The aim of this study was to identify knowledge of self-care behaviors and factors comp...

Introduction: Remission after transsphenoidal surgery in patients with acromegaly is confirmed by biochemical assays of growth hormone (GH) and insulin-like growth factor-1 (IGF-1). Although their levels are usually closely correlated, discordant results of these tests have been noted, making the follow-up of acromegaly patients particularly challenging.Case report: We present the case of a 35 year old female diagnosed with acromegaly at the age of 32 ye...

Introduction: Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy. It represents over 80% of all follicular derived well-differentiated thyroid cancers. Despite the fact that the majority of PTCs are well differentiated and have a low rate of local invasion, recurrences, or metastases, there are complex cases which require a multidisciplinary team for a favourable result.Methods: Clinical examination, blood tests, scintigraphy, CT s...

Introduction: Medullary thyroid cancer is a rare neuroendocrine tumor arising from the parafollicular C cells of the thyroid gland. Calcitonin production is a characteristic feature of medullary thyroid cancer and preoperative high levels indicate an increased risk of local and distant metastatic disease. Although rare, Horner syndrome could be caused by metastatic medullary thyroid cancer. Horner syndrome usually presents with ptosis, miosis and facial anhidrosis and most of ...

Background: Hypothyroidism affects cardiac function, leading to cardiomyopathy, pericarditis, lower left ventricular performance, etc. The present study investigates different parameters (clinical, hormonal, biochemical, echocardiographic) in overt primary hypothyroidism (OPHypo) and overt central hypothyroidism (OCHypo).Material and methods: The study included 33 untreated patients with OCHypo (5 with empty sella, 3 with idiopathic hypopituitarism, 7 wi...

Introduction: As antipsychotic drugs specifically block the D2 receptors, they induce a certain level of prolactin increase, dependent on the time it takes to dissociate from receptors. A recent review (Besnard et al, 2013) mentions that 18% of men and 47% of women treated with antipsychotics for severe mental illness had an increased prolactin level. Even if the long term effects of hyperprolactinemia can be severe, including low bone density, amenorrhea, breast and ...

Background: Primary hyperaldosteronism or Conn’s syndrome is one of the adrenocortical causes of hypertension, alongside hyperdeoxycorticosteronism, apparent mineralocorticoid excess and Cushing syndrome. The two types of hypertension-inducing adrenocortical syndromes (Conn’s and Cushing) are extremely rare to be decribed in the same patient. We describe a case of a patient with clinical and biochemical evidence of Conn’s syndrome due to a left adrenal adenom...

Panhypopituitarism refers to decreased production of all of the pituitary hormones of the adenohypophysis with or without deficiency of neurohypophysis function. The development of the disorder is frequently insidious and the manifestations often depend on the etiology of the condition.Case report: In October 2019 a 57-year-old man collapsed in front of the hospital after being discharged from the cardiology clinic. The day before, he had undergone angio...

Introduction: Although for the last 2 decades we have witnessed a rise in the use of second generation antipsychotic treatment in children and adolescents suffering from psychiatric disorders we do not have enough studies in specialty literature to estimate the risks associated with this medication. Recent data and also our clinical experience shows that second generation antipsychotic drugs administration correlates with considerable weight gain and also with altering of gluc...