Endocrine Abstracts

Craniopharyngiomas are rare lesions derived from cell remnants of Rathke’s pouch, usually localized in the sellar and suprasellar areas.Objectives: To analyze clinical, endocrine and histological features in a group of patients from Buenos Aires city. To assess efficacy, number of surgeries and complications after surgery or other treatments.Material and methods: Multicentric, retrospective, transversal study. Adult patients w...

A 52-year-old female patient with no previous history of interest, and with no prescribed habitual chronic treatment, was admitted to our hospital to be studied for symptomatic hypoglycemias of one month of evolution. Symptoms consisted of malaise, hunger, tremors and profuse sweating that disappeared with food ingestion. She referred hypoglycemic (up to 40 mg/dl) episodes daily, both in fasting and postprandial periods. She even suffered nocturnal episodes that woke her up. O...

Objectives: To evaluate the prevalence of eating disorders (ED) at an Endocrinology outpatient clinic (EOC); with the use of Bulimia Investigatory Test of Edinburgh (BITE).Methods: Descriptive analysis of clinical characteristics and BITE scores from patients with suspicion of ED at a first appointment in an EOC with an average of 128 new patients/year. Data was collected from January-2021 to December-2022. The main suspicion criteria were: self-reported...

A middle aged woman was admitted to Salisbury District Hospital after she was found to be severely hyponatraemic by her GP. She had been suffering from lightheadedness, headaches and tiredness for a few weeks before her admission but there was no obvious aetiology. Her past medical history included hypertension but she was not on diuretics or any other medication that could affect her sodium levels. Her serum sodium at the GP surgery was 123 and when she was admitted in the Ac...

Introduction: Several clinical and molecular markers can be used to establish risk at the time of diagnosis in DTC. Thyroglobulin (Tg), which is essential in follow up, could be an early marker to identify risk patients. Around 25% of patients require 18 months or longer to have indetectable Tg. The presence of Tg antibodies (TgAb) invalidate the follow up of DTC via Tg and this is usually associated with a poor prognosis.Aim: To evaluate the role of Tg ...

Pluripotent stem cells (PSC), both embryonic and induced (iPSC), are the most promising cell sources for replacement therapies. In particular for a disease like type 1 diabetes (T1D), caused by the loss of a single specific cell type that does not need to be transplanted back in its originating site to perform its function, a stem cell-based cell replacement therapy seems to be the ideal cure. At present, however, a successful strategy for the use of PSC in patients with diabe...

Neuroendocrine tumours (NETs) are heterogeneous neoplasm, arising from different endocrine cells distributed in many organs and tissues which share a common neuroendocrine phenotype. The neuroendocrine cells of the human body are confined to certain organs such as thyroid, pancreas or adrenals, or are dispersed throughout the body in the respiratory tract and abundantly in the intestinal mucosa. These cells belong to the diffuse endocrine cell system, which is the largest endo...

Background and Aim: The incidence of papillary thyroid microcarcinoma (mPTC) has dramatically increased in the last decades. The majority of these tumors remain small and clinically silent, only small number progress. Clinical practice guidelines currently suggest avoiding the cytological examination of subcentimeter nodules and reducing surgeries for mPTC. Several risk factors have been identified as strongly associated with a high-risk phenotype for mPTCs (e.g. gross nodal m...

A 52-year-old male patient with no past medical history of interest was admitted to our Endocrinology Unit with a clinical course developed in the last month of sudden polyuria, nocturia and polydipsia (8 liters/day) associated with bilateral low back and leg pain, a right-side nasal congestion with eye swelling and paresthesia. Physical examination revealed a doubtful thickening of the nasal mucosa and several two-cm- scattered erythematous disseminated skin lesions. Blood sa...

Background: PREDIRCAM2 is a web platform for obesity treatment and follow-up. It contains modules for: dietary prescription and registry with nutritional analysis based on individualized and mediterranean dietary goals, physical activity prescription and tracking with individualized targets, and anthropometric tracking. An ongoing multicenter randomized clinical trial evaluates the intervention’s effectiveness in obesity treatment and cardio-metabolic-risk prevention....