Endocrine Abstracts

Hypoglycaemia continues to be a difficult condition to treat especially in infants and young children who cannot administer treatment themselves. Administering the correct dose of sugar is difficult for several reasons: the child may not want to intake food and it may be difficult to force the child to chew or swallow, it is difficult to identify the quantity of sugar necessary to reach optimal glucose levels. If too much sugar is administered, high levels of blood glucose may...

It is a real honour to be named Outstanding Clinical Practitioner by the Society for Endocrinology, especially as I am sharing this with my award twin, Professor Kristien Boelaert. For my presentation I will talk about aspects described in the nomination and discuss how improving patient care is at the heart of all we do. This can be achieved at an individual patient level, organisational level, and a national systems level. I will describe work around the NHS steroid emergenc...

Oestrogens are formed in the ovary from androgen precursors which circulate at a higher concentration in the blood and have a greater production and secretion rate than oestrogens. Although the post menopausal ovary remains a source of testosterone (T) production there is a fall in total circulating androgens with age and this results from a combination of ovarian failure, decreasing adrenal secretion and peripheral conversion.This relative androgen deficiency is greater in wo...

During this session I will discuss some ways of approaching requests for interviews by the media. The media can be main stream media such a television or radio, social media such as Twitter or web based journals. It can be daunting to consider having your views for all to see or hear, however there are many reasons to engage with the media. I will discuss some strategies on how to react to requests for information and offer some suggestions on how to approach interviews and me...

Oestrogens are formed in the ovary from androgen precursors which circulate at a higher concentration in the blood and have a greater production and secretion rate than oestrogens. Although the post menopausal ovary remains a source of testosterone (T) production there is a fall in total circulating androgens with age and this results from a combination of ovarian failure, decreasing adrenal secretion and peripheral conversion.This relative androgen deficiency is greater in wo...

During this session I will discuss some ways of approaching requests for interviews by the media. The media can be main stream media such a television or radio, social media such as Twitter or web based journals. It can be daunting to consider having your views for all to see or hear, however there are many reasons to engage with the media. I will discuss some strategies on how to react to requests for information and offer some suggestions on how to approach interviews and me...

Children referred to paediatric endocrinology clinics have variable degrees of short stature and growth failure. There is a wide range of potential aetiologies ranging from normality to an abnormal growth pattern which will lead to adult height below the target height range. Early investigation and diagnosis of short stature is important to prevent delays in the access to appropriate therapies which will improve final height. Genetic variants impacting cellular pathways, hormo...

Immune checkpoint inhibitors are a new group of monoclonal antibodies against checkpoints in normal T Lymphocyte activation enabling immune system activation in order to target cancer cells. First used for treatment of melanoma in 2011, they are currently indicated for management of an increasing spectrum of malignancy. Endocrinopathy secondary to checkpoint inhibitors is commonly observed. This has led to a new group of patients requiring specialist investigation, management,...

Background: Hyponatraemia is the most frequent electrolyte disturbance in hospitalised patients and is associated with increased morbidity and mortality as well as increased expenditure. Hyponatraemia is a common reason for referral to Endocrinology in the hospital setting however hyponatraemia has a variety of causes many of which do not come under the remit of ‘Endocrinology’.Aim: To determine the aetiology of severe hyponatraemia in hospital...

Practical points regarding the diagnosis and management of conditions affecting the vulva in childhood and adolescence. This includes history-taking, examination, investigation, clinical diagnosis and treatment....