Endocrine Abstracts

Background and aimsMetabolic syndrome (MetS) is a pathologic condition characterized by abdominal obesity, insulin resistance, hypertension, and dyslipidemia. The prevalence of MetS parallels the rise of obesity rate reaching pandemic proportions due to the increased consumption of high-calories-high-fat-high-carbohydrates low-fibers diet associated with a sedentary lifestyle. MetS is associated with a plethora of comorbidities as non-alcoholic fatty liv...

Introduction: Hyponatraemia is the most common of electrolyte abnormalities. There are numerous factors which may directly cause or contribute to hyponatraemia, including dehydration, concomitant cardiac/hepatic/renal disease, and certain medications, such as diuretics. Hyponatraemia may cause a range of symptoms, depending on the speed and severity of the deficiency. Mild hyponatraemia (>115 mmol/l), can causes malaise, nausea and vomiting. Significant hyponatraemia, [Na<...

Primary adrenal failure is a rare condition with an incidence during pregnancy of around 1 case in 12 000 gestations.A 31 years old primi gravida presented 10 days after giving birth to a healthy child at full term with postural dizziness and severe fatigue. There was no history of excessive blood loss during delivery and her past medical history was unremarkable, but low blood pressure (BP) was reported throughout pregnancy. She mentioned increased body...

Introduction: It has been seen that Zoledronic acid (ZA) infusion induces an acute inflammatory response associated with rise in inflammatory markers and changes in thyroid function tests resembling non thyroidal illness syndrome. It is also postulated that amino group of ZA has a role in causation of these thyroid function abnormality. (1)Material and methods: An observational study at tertiary care hospital of India where thyroid functions tests were s...

Background: An endocrine disruptor is an exogenous chemical or mixture of chemicals that interfere with any aspect of hormone action. It can interfere with the body’s endocrine system and produce adverse cardiovascular, neurological, developmental, reproductive, and metabolic effects in humans. This study aims to evaluate the knowledge, attitude, and practices (KAP) of the medical students regarding the exposure, usage, and long-term harmful effects of Endocrine Disrupt...

Background: The aim of study was to determine the effectiveness of Thyroid detoxification program therapy in patients of hypothyroidism, attending TATC clinic in Maharashtra. According to the clinical survey from various studies on thyroid disease, it has been estimated that about 32% of people suffer from thyroid diseases in India out of which 10.7 % of people have hypothyroidism. According to health experts, even though hypothyroidism is easy to detect and inexpensive to tre...

Objective: To demonstrate the effectiveness and compliance to L-thyroxine in the treatment of hypothyroidism in a weekly dose of seven times of normal dose as an alternative to daily dosing in young and middle aged females.Methods: Randomized trial on 40 female patients aged between 25 to 55 years with long standing hypothyroidism of 5 years or more, currently on daily dose of L-thyroxine, were assigned weekly dose of seven ...

Objective: To evaluate the effectiveness of low frequency pulsed electro magnetic field (LF-PEMF) in the management of diabetic peripheral neuropathy (DPN) symptoms.Methods: A comparative observational study of 60 patients, male and female (1:1) aged 60–85 years. Enrolment criteria – known diabetics, HbA1c 7–9 and DPN of 1–5 years. Patients were randomized into 2 treatment groups G1 and G2. The study period was 4 weeks (w) with result...

Objective: To evaluate the effectiveness of low frequency pulsed electro magnetic field (LF-PEMF) in the management of diabetic peripheral neuropathy (DPN) symptoms.Methods: A comparative observational study of 60 patients, male and female (1:1) aged 60–85 years. Enrolment criteria – known diabetics, HbA1c 7–9 and DPN of 1–5 years. Patients were randomized into 2 treatment groups G1 and G2. The study period was 4 weeks (w) with result...

Objective: To evaluate the effectiveness and compliance to L-thyroxine in the treatment of Hypothyroidism in a weekly dose of 7 times of normal dose as an alternative to daily dosing in young and middle aged adults.Methods: A randomized prospective observational study on 180 patients (female:male) ratio of 5:1 aged between 18 and 55 years with an established diagnosis of Hypothyroidism were assigned a weekly dose of seven times of normal dose. The patien...