Endocrine Abstracts

A 48-year-old woman presented to her GP with polyuria and proximal muscle weakness. She was found to have newly developed hypertension at 180/96 and her serum potassium was 2.7 mmol/l. Lisinopril 40 mg od and Slow-K 1 tablet bd were started and she was referred for further investigation.On clinic review blood pressure was 188/110 supine and 190/110 standing. Serum sodium was 147 mmol/l, potassium 3.7 mmol/l and total bicarbonate 29 mmol/l. Her Lisinopril...

The epidemic nature of obesity/overweight throughout the developed and less-developed world suggests that major new influences are at play. Correct identification of these influences must precede discussion of what action can rationally be planned. The widespread failure to recognise that this problem concerns the whole population and not merely those with a BMI over the arbitrary normal level is a critical factor in appreciating the nature of the problem. The lack of efficacy...

The epidemic nature of obesity/overweight throughout the developed and less-developed world suggests that major new influences are at play. Correct identification of these influences must precede discussion of what action can rationally be planned. The widespread failure to recognise that this problem concerns the whole population and not merely those with a BMI over the arbitrary normal level is a critical factor in appreciating the nature of the problem. The lack of efficacy...

The cyp19 encodes cytochrome P450aromatase, the key enzyme catalyzing the conversion of androgens to estrogens. Estrogens play a critical role in controlling functional, behavioral and physiological aspects of sexual development both in males and females. Except in Anguilla anguilla, most teleosts studied so far possess two cyp19 genes namely, cyp19a and cyp19b; ovary- and brain-specific respectively. In the present study made in tw...

Issues: Adolescent diabetes social stigma in India. Such diabetics needs proper guidance/information/treatment-counselling outlets. This is burning issue in developing-nations like India. Hence we all need to unite & form a comprehensive diabetes care & counselling policy plan at ECE conference. Treatment options must be suitable for developing-nations considering cost of Rx. Incorporating NGO’s in such efforts is very effective.Our Project ...

Adrenal cortical carcinoma (ACC) is extremely rare, the incidence is 0.5 - 2 cases per million populations per year. Most ACCs occur as sporadic tumours. It is more common in females and can occur at any age with a peak in fifth and sixth decades of life. We present a 45-year-old otherwise well and fit lady presented with headache, lethargy, and two stone rapid weight gain over a period of 6 months. She also had associated nocturia, insomnia, night sweats, hirsutism, and acne....

Case Information: A 39-year-old woman from Guatemala with no significant past medical history initially presented with swelling in neck & obstructive symptoms. She was diagnosed with papillary thyroid carcinoma in March 2017 & underwent a total thyroidectomy& LN Dissection. Pathology showed multifocal, largest tumor size 3.2 cm, with one involved lymph node, significant angiolymphatic invasion, and was stand was staged as initially received 121 mCi of radioactive i...

Regulation of thyroid hormone (TH) levels in blood is controlled by feedback at the level of the pituitary and hypothalamus. It has been suggested that the set-point of either turning on or off the release of TSH and TRH, respectively is due to multiple factors including intrauterine exposure to TH. We have utilized the TH receptor (TR) β disrupted mouse (TRβ−/−) as model to study the effect of maternal levels of TH on newborn thyroid function. The ration...

Cushing’s syndrome can lead to various complications, including pathological fracture. As an initial presenting symptom pathological fracture is not very common in Cushing’s syndrome. This abstract aims to present a case study of a female patient with multiple pathological fractures at a young age and subsequently diagnosed with Cushing’s syndrome. A 32-year-old female (at the time of referral) after a stress fracture of the right neck of the femur without any t...

Issues: In developing nations diagnosis of diabetes brings mental-trauma/depression in family. Focused treatment for pediatric age-group is unavailable in developing-countries. 26% of diagnosed diabetics are children’s. Adequately trained physicians/Nurses in issues of pediatric-diabetes provide continuity of care, relief from depression and smooth transition from diagnosis to treatment. Qualitative collaborative relationship between these makes diabetics life bearable. O...