Endocrine Abstracts

Introduction: Thyroid nodule is a common disease that is found in 50% of the adult population; of total, 5% of thyroid nodule cases are diagnosed as thyroid cancers. Thyroid ultrasonography is the most sensitive diagnostic imaging method for the diagnosis of thyroid cancer. The ultrasonographic findings that indicate malignancy are taller than wider, speculate margins, marked hypoechoic lesion, microcalcification, and macrocalcification. In contrast to findings indicating pure...

Background: Radiofrequency ablation has recently been used for the treatment of benign thyroid nodules, with outstanding results. However, in most related studies, smaller nodules (<2 cm) were included and the procedure was usually performed by a radiologist or surgeon. Therefore, this study evaluated the efficacy and safety of radiofrequency ablation for nodules >2 cm performed by an endocrinologist with several years of experience performing fine-needle aspiration cy...

Background: Most thyroid nodules are benign therefore, they are commonly only monitored. Only a few studies are available on the natural progression/regression of benign thyroid nodules, and large-scale studies on the subject are non-existent. So we identify factors that affect the size of benign thyroid nodules and to predict the potential nodule size through a model.Methods: Between January 2001 and December 2011, 2,469 benign thyroid nodules (1,564 pa...

Aims: Diabetes is an important health condition in the aging population. The risk of depression is increased in older adults and should therefore be screened and managed. Especially, it is important to early detect and improvement of depression in older adults with diabetes because it is associated with glucose control and development of diabetic complication. We evaluated the prevalence of depression in diabetic older adults and identified associated independent risk factors ...

Diabetic peripheral neuropathy (DPN) is a most common complication of diabetes mellitus. Patients with DPN have chronic, painful symptoms that disrupt sleep, depressed mood and can lead to diminish quality of life. We evaluated clinical characteristics of diabetic peripheral neuropathy in past and present in KoreaWe performed the study to determine the prevalence and to understand the clinical characteristics of diabetic peripheral neuropathy in Koreans ...

Background: The tall cell variant (TCV) of papillary thyroid carcinoma (PTC) (TCVPTC) is the most common aggressive variant of PTC. Classic PTC with tall cell features (TCF) is defined as PTC with noticeable tall cells but the percentage of these cells is lower than that required for the diagnosis of TCVPTC. We aimed to investigate the potential differences between TCVPTC and classic PTC with TCF with respect to clinicopathological characteristics and long-term oncologic outco...

Introduction: The purpose was to compare aqueous inflammatory and angiogenic cytokine levels in diabetic macular edema (DME).Methods: Aqueous samples were obtained from 50 eyes with DME and 12 normal eyes (control group). DME was classified according to the morphologic pattern based on optical coherence tomography: Diffuse retinal thickening (DRT; n=19), cystoid macular edema (CME; n=17), or serous retinal detachment (SRD; n=14...

Introduction: We report a case of diabetic papillopathy that demonstrated a resolution of optic disk swelling and rapid visual recovery when intravitreal ranibizumab was administered.Case report: A 51-year-old male presented with acute painless visual loss in his right eye. His vision was 20/320 in the right eye and 20/50 in the left eye. Fundus examination of the right eye showed nonproliferative diabetic retinopathy with macular edema and a swollen opt...

Background: Thyroid cancer has been increasing worldwide and became one of the most popular cancer. Recent reports have shown that an elevated thyrotropin(thyroid stimulating hormone, TSH) level is associated with risk of thyroid cancer. Nevertheless, the association between TSH level and thyroid cancer risk is not yet known in patients diagnosed with papillary thyroid microcarcinoma (PTMC).Methods: We collected cases of 212 patients who underwent thyroi...

Familial benign hypocalciuric hypercalcaemia (FHH) is a lifelong, benign, inherited condition with slightly increased levels of plasma calcium, low urinary calcium excretion, and normal to moderately elevated plasma parathyroid hormone (PTH). In most cases, FHH (type-1) is caused by inactivating mutations in the gene encoding the calcium sensing receptor (CASR) expressed in the parathyroids and the kidneys. The estimated prevalence of FHH is 1 in 78 000 compared with that of p...