Endocrine Abstracts

The Sheffield Children’s Diabetes Team [SCDT] look after approximately 240 patients with Type 1 Diabetes aged 0–17 years. We have approximately 35 newly diagnosed patients each year and the level of social deprivation amongst our clinic population is high. Historically the team has always performed well in terms of measured outcomes and in the 2014–2015 National Paediatric Diabetes Audit [NPDA] data we ranked amongst the top five units in the country with a mean...

Introduction: Currently group education facilitation skills are not part of foundation nurse, medical or dietetic training. Additionally there is no nationally recognised evidence based structured education programme for paediatrics which meet the DoH criteria (2005). Consequently paediatric diabetes teams cannot access group facilitation skills through programmes such as DAFNE and DESMOND in contrast to colleagues working with adults. A one day workshop on group facilitation ...

Men and women who have AIS face a number of challenges. Based on research insights from the past two decades, management of this pleiotropic condition during childhood has totally changed. In this presentation, we will update endocrinologists who provide care for adults living with AIS about these changes, as they will, after transition, need to further counsel their patients and coordinate multidisciplinary care and surveillance of retained gonads in adulthood. Girls with com...

Background: Patients and carers encounter a range of diabetes multi-disciplinary team (MDT) members. Patients in focus groups have indicated that nurses are more approachable than doctors1, and the presence of specialist nurses in the MDT improves glycaemic control2. Nurses are perceived to be the core providers of diabetes care but this has not been quantified, nor have the perceived roles of other members of the MDT been explored....

Bardet-Biedl syndrome (BBS) is a heterogeneous autosomal recessive disorder characterized by obesity, retinopathy, cognitive abnormalities, and polydactyly and other congenital anomalies. Patients also have an increased incidence of hypertension and diabetes. Mutations in at least 14 genes have been reported to independently cause BBS. In order to better understand the pathophysiology of BBS, we have generated BBS mouse models and have investigated the interaction of the prote...

Background: Chromosome analysis is always indicated in disorders of sex development (DSD), but the need for karyotyping in gender dysphoria (GD) is less clear.Aims and objectives: We therefore aimed to review the place of routine chromosome analysis in the management of GD in children and adolescents.Patients and methods: Five hundred and twenty children and adolescents with GD have been referred at the time of reporting to the two...

Background: Primary hyperaldosteronism (PH) is a syndrome caused by excess aldosterone secretion, which leads to hypertension and hypokalemia and increased risk for target organ damage. The overproduction of aldosterone at the adrenal gland can be unilateral or bilateral. For unilateral disease the best treatment is unilateral adrenalectomy. According to international guidelines, most of the patients should have adrenal venous sampling (AVS) to distinguish between bilateral an...

Background: There may be a bidirectional association between glycaemia and pNETS. Pre-existing diabetes mellitus(DM) is a recognised risk factor for the development of pNETS. Prevalence of DM in pNETS has been reported as 12-26% depending on patient age and tumour location. DM due to pNETS is classified as type 3C pancreatogenic diabetes, Type 3D caused by hormone disorders or Type 3E induced by medications. Functional pNETS, medical therapies and pancreatic s...

In September 2021 the pathology department announced it would be going paperless, a change that resulted in endocrine monitoring being added to the trust risk register. To manage this risk several options were considered including the DAWN system used by rheumatology and systems used by other local hospitals. Unfortunately, none of these were viable options. Discussions were started with the IT systems development team about building a database for management of thyroid patien...

NOTICE OF RETRACTION: This abstract is retracted at the request of the author.This study aimed to re-audit the surgical and medical treatment of acromegalic patients in the Sussex Pituitary Multidisciplinary Team (MDT). This involved assessing biochemical control and treatment complication rates. The study compared treatment outcomes with previous 2010 audits and national published standards. Fourty patients (25 males, aged betwe...