Endocrine Abstracts

Background: CGM based monitoring can help in development of personalized digital therapeutics programs based on the understanding of the effect of diet, physical activity and medications on everyday blood glucose excursions. The variation in intra-individual glycemic response to the same food has been reported in many studies. Thus, understanding of personalized glycemic response (PGR) of each individual becomes important for effective diabetes management.<p class="abstext...

Background: Managing the relentless requirements of diabetes management can lead to an increase in distress among people with diabetes. There is a need for feasibility studies to understand the effectiveness of multi-disciplinary care delivered using digital therapeutics interventions to provide effective glycemic control along with improved overall well-being of individuals. The study aims to evaluate the feasibility and effectiveness of the Fitterfly diabetes program to impr...

Background: People with chronic metabolic conditions such as type 2 diabetes (T2D) encounter challenges with self-management regimens to improve their glycemic control, weight and as well as to reduce complications associated with diabetes. Optimal management of T2D requires regular monitoring by physician, access to multidisciplinary care and achieving target HbA1c without hypoglycemia. Digital therapeutics (DTx) provide highly accessible, cost-effective, evidence-based solut...

Background and aim: Early glycemic control and weight reduction in diabetes has been associated with prevention of progression of β-cell dysfunction and reduction in diabetes-related complications. Digital therapeutics (DTx) platforms can provide evidence-based therapeutic interventions to improve glycemic control using sustainable behavior change. This study aims at assessing the real-world effectiveness of the Fitterfly Diabetes program in improving glycemic control and...

45/M presented to hospital with h/o assault on head (hit by meat cleaver). Background history of drug abuse and previous drug induced psychosis. Trauma CT head revealed mass in the enlarged pituitary fossa. MRI head revealed 5 x 4 cm mass in the sella turcica encasing the internal carotid vessels but sparing optic chiasma. Visual field examination was normal and no other clinical symptoms were present. Serum prolactin was 67922. Tumor was not for resection so medical treatment...

A 40 y /M with no previous CVS/family history, presented with fall. On history, he was feeling unwell, had Appetite loss × 3 months, progressive SOB, Orthopnoea, PND and palpitations. No chest pain/fever. On Examination, he had tachycardia (160) and irregular rhythm, raised JVP, SpO2 92%, B/l ankle edema, bibasal fine inspiratory crackles in chest, Hepatomegaly(3 cm) CVS :S3 gallop, mild TR, MR. ECG: sinus rhythm with freq ectopics, long QT, paroxysms of tachycardia, T wa...

Context: NICE and BTA agrees that combination L T4 and LT3 can be used in patients with symptoms persisting after adequate use of LT4.Methods: We retrospectively audited the patients coming to the endocrine clinics of ESHT whether they followed the local agreed protocol of LT3 usage. We checked if they had:1. Initiation of LT4 by an endocrine specialist.2. If other causes of tiredness were ruled out.<p cl...

Introduction: Precocious puberty occurs is associated with initial increase in linear growth and acceleration of bone maturity presenting as advanced bone age with early epiphyseal fusion which ultimately results in short stature. ‘Van Wyk Grumbach Syndrome’ (VWGS) is a rare syndrome associated with incomplete isosexual precocious puberty and macroadenoma seen in cases of longstanding, untreated hypothyroidism is associated with a delayed bone age. Complete resolutio...

Type I diabetes mellitus (DM) is characterized by an autoimmune destruction of the pancreatic β-cells that leads to absolute insulin deficiency. However, T1DM individuals undergoing exogenous insulin therapy may show partial remission of endogenous insulin secretion and better insulin sensitivity, and this remission may range between few months to many years. This partial remission is known as the ‘honeymoon phase,’ and extending the duration of this remission h...

Despite conventional treatment with oral calcium and active vitamin D, patients with chronic hypoparathyroidism (cHypoPT) can remain not adequately controlled (NAC) and have abnormal biochemistry, disease complications, or symptoms impacting quality of life. A systematic literature review (SLR) was conducted to evaluate the clinical burden for patients with cHypoPT, with an emphasis on patients with NAC disease. This abstract focuses on data related to renal and cardiovascular...