Endocrine Abstracts

Introduction: The effect of aldosterone levels on the severity of arterial hypertension was established in many studies. Changes in the level of aldosterone can lead to disorders of the cardiovascular, nervous, excretory systems. One of the factors affecting the fluctuation of aldosterone is the presence of adrenal gland mass.Aim: To check for a correlation between the identified adrenal masses and the severity of arterial hypertension against the backgr...

Introduction: Despite the emergence of all new means of control and treatment of type 1 diabetes (T1DM), the achievement of target indicators of glycemia remains a serious problem, which leads to the development of chronic complications. Therapeutic training of the basics of life with diabetes allows patients with T1DM to improve glycemic control.Target: Evaluate the influence of individual learning at the Diabetes School on HbA1c....

Introduction: SARS-COV-2 is a new infection with little known consequences. As data accumulated, it became known that the thyroid gland is also affected as a result of infection. During the reconvalescence period, some patients developed severe thyrotoxicosis, which did not have the classic clinical picture of subacute thyroiditis or autoimmune.Aim: To study the course of subacute thyroiditis in patients after infection with COVID-19.<p class="abstex...

The article is devoted to one of the most pressing medical problems – diabetes mellitus type 2.Objective: To study the peculiarities of the course of diabetes mellitus type 2 in persons over 65 years of age; to evaluate the effectiveness of different therapy regimens for the level of HbA1C.Material and methods: The retrospective study included 100 patients with type 2 diabetes (T2D). The age of the patients: 65 to 82 years. Th...

Introduction: The presence of diabetes-associated antibodies is an indicator of β-cell destruction. Our goal was to find out the prevalence of autoantibodies associated with the new onset of type 1 diabetes mellitus (DM1) without family history.Subjects and Methods: 22 patients (10 women and 12 men) with newly diagnosed DM1 no family history were examined. Average age of patients was 31.7&pm;7.3 y.o., experience of DM1 was 2.3&pm;0.8 months. All the...

Background: Attendance and active participation in diabetes school classes is an important element in disease management. It has been noted that self–learning and self–help predetermine the clinical outcomes of diabetes and the quality of life of patients.Aim: To evaluate the awareness of patients with type 2 diabetes (T2D) about their disease.Materials and methods: 45 patients with T2D were included. The survey contain...

Background: Diabetic nephropathy (DN) is a major cause of morbidity and mortality in type 1 diabetes (T1D) patients and associated with increased cardiovascular risk in type 2 diabetes (T2D) patients. Early detection of DN using neutrophil gelatinase-associated lipocalin (NGAL) assessment can help to reveal predisposed patients to its progression and to prevent progression of DN. Especially important it is in patients with normoalbuminuria.Aim: To determ...

Introduction: Preserving of C-peptide secretion in type 1 diabetes mellitus (DM1) is an important goal in treatment, as it provides the possibility of optimal compensation. Various approaches are used to achieve this goal. We initiated a study to assess the potential effect of the cell therapy based on autologous Tolerogenic Dendritic Cells on the newly diagnosed DM1 (NCT05207995, ClinicalTrials.gov).Methods: 4 patients who were injected with Tolerogenic...

Introduction: Glutathione system prevents oxidative stress development in erythrocites. When this system becomes depressed it predisposes a cell to apoptosis.Aim: To study glutathione system status in patients with diabetesMaterials and methods: Included patients were divided into four groups: group 1–41 almost healthy person (control group), group 2–41 patients with type 2 diabetes (T2D), group 3–40 patients with T2...

Introduction: Glutathione system prevents oxidative stress development in erythrocites. When this system becomes depressed it predisposes a cell to apoptosis.Aim: To study glutathione system status in patients with diabetesMaterials and methods: Included patients were divided into four groups: group 1–41 almost healthy person (control group), group 2–41 patients with type 2 diabetes (T2D), group 3–40 patients with T2...