Searchable abstracts of presentations at key conferences in endocrinology

Endocrine Abstracts

Published by BioScientifica

Page 1 of about 177 results

ea0063p445 | Adrenal and Neuroendocrine Tumours 2 | ECE2019

11C-Metomidate PET/CT Identifies Unilateral Primary Aldosteronism in a Multi-ethnic Cohort

Puar Troy , Tan Colin , Tong Aaron , Zhang Meifen , Khoo Chin Meng , Tan Alvin , Htoo Htoo , Reilhac Anthonin , Weekes Ashley , Robins Ed , Foo Roger

Introduction: Patients with unilateral primary aldosteronism (PA) can be cured with adrenalectomy, and adrenal vein sampling (AVS) remains the gold-standard test. However, AVS is invasive, technically-challenging and criteria for determining lateralization differ between centres. 11C-Metomidate PET/CT (MTO) imaging offers a promising non-invasive alternative for identifying unilateral PA.Methods: All patients with confirmed primary aldosteronism who were...
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ea0035gh1biog | The Geoffrey Harris Prize Lecture | ECE2014

Geoffrey Harris Prize Winner

Grossman Ashley

This prestigious prize is intended for established workers in the field of basic and clinical neuroendocrinology and is generously supported by Ipsen. This year’s recipient is Prof. Ashley Grossman. The prize will be presented as part of the ECE 2014 opening ceremony where Prof. Grossman will deliver his lecture. Prof. Grossman will also deliver two other lectures at future ESE scientific meetings. Further information can be found at <a href="http://www.ese-hormones.org/p...
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ea0059p206 | Thyroid | SFEBES2018

Iodine restricted diet prior to radioiodine therapy for hyperthyroidism

Nabi Assad , Weekes Joanne , Krishnasamy Senthilkumar , Buch Harit

Background: There has been conflicting evidence on the use of strict dietary iodine restriction prior to Radioiodine (RAI) administration for the management of hyperthyroidism and varying level of restrictions have been used. More recently the Medical Physics team in our institute implemented strict dietary iodine restrictions for 2 weeks pre-RAI administration. Significant inconvenience was reported by patients, which in some instances led to their reluctance to receive a sec...
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ea0094p394 | Thyroid | SFEBES2023

Use of TRAB values to predict the need for second dose of Radio-iodine therapy (RAIT)

Dodiya Manoj , Weekes Joanne , Kalaria Tejas , N Buch Harit

Background and Aim: RAIT is successful in achieving cure of thyrotoxicosis. However, 10-15% patients require further doses, usually administered at 4-6 months after the initial dose. We assessed the role of TRAB values in predicting the need for redosing, which could have useful implications.Patients and Methods: We measured TRAB at diagnosis and at the time of 550MBq RAIT in 54 patients with Graves’ disease. We rec...
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ea0086ns1.1 | Neuroendocrine tumours | SFEBES2022

The management of neuroendocrine tumours

Grossman Ashley

Neuroendocrine tumours, or NETs, are a heterogeneous group of tumours which may arise from many sites, but primarily from the gastro-entero-pancreatic (GEP) system, and the respiratory system as bronchial and occasionally thymic NETs. Many small NETs are diagnosed incidentally as appendiceal or gastric NETs, and generally act in a totally benign manner. Diagnosis is contingent on positive histopathology (positive chromogranin immunostaining, grading 1-3 based on the Ki-67 inde...
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ea0059se1.3 | (1) | SFEBES2018

Why did the Queen die?

Grossman Ashley

In 1547 Henry VIII died, and was succeeded by his young son from his marriage to Jane Seymour; the boy was only 9 years old, and became Edward VI. However, he was a sickly child, and only survived to the age of 15 years, probably dying of TB. With no living male heir, there was an attempt at continuing with a Protestant monarch, but this lasted only 9-days with the unfortunate Lady Jane Grey. The crown then fell to Mary, the child of the marriage of Henry to Catherine of Arago...
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ea0038mte9 | (1) | SFEBES2015

Grossman Ashley

The term pituitary tumour usually implies an adenoma arising from anterior pituitary tissue, but in fact some 2–5% of ‘tumours’ in this region are not adenomas, and many of these arise from the para-sellar region or within the hypothalamus. One clue as to the non-adenomatous origin of such tumours is the presence of diabetes insipidus, which is almost never present with a primary pituitary adenoma. Some 1% of sellar masses are metastases, most often from the fre...
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ea0032s17.1 | Medical treatment of endocrine malignancies - an update | ECE2013

Pituitary carcinoma

Grossman Ashley

Pituitary tumours have recently been shown to have a prevalence of around one in a 1000, but the overwhelming majority of these are benign and readily treated. Nevertheless, while the initial therapy of the majority of non-secreting macroadenomas is transsphenoidal surgery, these have a high tendency to recur; recurrence cannot at present be predicted by any histopathological markers. Indeed, some 50% of such adenomas will recur over 10 years, although this recurrence rate is ...
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ea0031mte6 | (1) | SFEBES2013

Malignant phaeochromocytomas

Grossman Ashley

The great majority of phaeochromocytomas are benign, but some 10–15% are found to be malignant, the proportion being higher when they are extra-adrenal, paragangliomas. Malignant behaviour is hard to predict, and there are few histopathological features that are consistently of use. There are novel biochemical and molecular markers, but none has proven to be as yet especially reliable although elevated urinary methoxytyramine seems to be useful. At present, size is proba...
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ea0020s21.4 | Current problems in the management of pituitary tumours | ECE2009

Treatment options for aggressive pituitary tumors

Grossman Ashley

Pituitary tumours have recently been shown to have a prevalence of around one in a 1000, but the overwhelming majority of these are benign and readily treated. Nevertheless, while the initial therapy of the majority of non-secreting macroadenomas is transsphenoidal surgery, these have a tendency to recur even when apparently totally removed. Recurrence seems not to depend on dural invasion, and it cannot at present be predicted by any histopathological markers. Indeed, some 50...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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