Endocrine Abstracts

Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting approximately 4–8% of premenopausal women. The main clinical features are clinical and/or biochemical hyperandrogenemia, oligomenorrhea and polycystic ovarian changes. It has gained a great attention during the last two decades with the realization that this syndrome affects more than the reproductive system. Epilepsy is a common neurologic disorder affecting women during the reproductive years. Sei...

Aim: Bisphenol A (BPA) is the most common endocrine disruptor among environmental estrogens. BPA is an ingredient that is commonly used in polycarbonate plastics. In this study, our main concern is to measure the levels of BPA in premenopausal obese women and to examine the relationship of BPA with adiponectin and leptin.Materials and methods: 47 obese women and 39 non-obese healthy women were enrolled in this study. All participants were premenopausal. ...

Rhabdomyolysis is a syndrome characterized by muscle necrosis and the release of intracelluler muscle contents into systemic circulation. It can became a life-threatening disorder when complicated by acute tubuler necrosis and renal failure. Fenofibrate, a fibric acid derivate, is used to treat diabetic dyslipidemia, hypertriglyceridemia and combined hyperlipidemia alone or in combination with statins. Rhabdomyolysis associated with fenofibrate is extremely rare. In nearly all...

Objective: We aimed to determine the risk of hypercalcemia in a geriatric population with very high dose levels of 25-hydroxy-vitamin D (25(OH)D)Patients and Method: This study was designed as a retrospective, cross-sectional two-center study for examining the elderly patients with very high 25(OH)D levels (>88ng/ml) between January 2014 and December 2019. After recruitment, subgroup analyses of the patients were performed based on their calcium and ...

Objective: The frequency of differentiated thyroid cancer in the Graves’ disease are controversial. The aim of this study was to evaluate the frequency of thyroid cancers in patients operated because of Graves’ disease.Subjects and methods: Sixty-six patients in whom thyroidectomy was performed because of Graves’ disease between 2001 and 2012 were evaluated retrospectively. Patients who had received radioactive iodine treatment and externa...

Introduction: The most common cause of diabetes insipidus is idiopathic. However, it may be also seen after metastasis to hypothalamic–pituitary region.Case: Fifty year old female patient with breast cancer was referred to our clinic with complaints of polyuria and polydipsia. Two years ago, she had diagnosed and after surgery, she has taken three cycles of cyclophosphamide+adriamycin+5-flurourasil than three cycles dosetaxel and finally seventeen c...

Introduction: Oncocytic tumor of adrenal gland was defined as a neoplasm composed exclusively or predominantly of oncocytes which are large and polygonal cells with eosinophilic cytoplasm because of abnormal accumulation of mithochondria. Oncocytic neoplasms of the adrenal cortex are extremely rare and are usually non-functioning, benign and incidentally detected.Case: A 40-year old male patient, for whom a large mass in the adrenal gland was diagnosed i...

Aims: Glycosylated hemoglobin (HbA1c) is a marker which demonstrates 3-month average level of blood glucose level. In individuals with high blood sugar level for a long time is associated with increased risk of cardiovascular disease (CVD). There is a need for simple and cost-effective markers to determine the risk of CVD in primary health care settings. In this study, we aimed to investigate the value of HbA1c for predicting cardiovascular risk in healthy non-diabetic individ...

Human chorionic gonadotropin bears structural homology to pituitary thyrotropin. The extremely elevated levels of human chorionic gonadotropin in patients with molar pregnancy or other trophoblastic diseases can lead to hyperthyroidism. We describe a patient with molar pregnancy who had secondary hyperthyroidism prepared rapidly by plasmapheresis for surgery. After first plasmapheresis the clinical picture improved dramatically. Three subsequent plasmapheresis provided a 75.1%...

A 76 year old man known to have coronary heart disease, hypertension and chronic kidney disease due to hypertensive nephropathy admitted to the nephrology clinic with fatigue, nausea and dizziness. His creatinine level was detected to be increased (from 1.5 to 2.5 mg/dl) and was he was hospitalized. The cranial magnetic resonance imaging (MRI) performed after neurology consultation for dizziness showed a pituitary mass. When asked, the patient described bitemporal hemianopsia ...