Endocrine Abstracts

Background: Hypovitaminosis D is associated with poor dietary intake and inadequate sunshine exposure. It is common worldwide. However, recent studies has shown a high prevalence of hypovitaminosis D in Moroccan population.Objective: We undertook this study to determine the specific prevalence of hypovitaminosis and its relationship to metabolic parameters in pre-menopausal women living in a sunny region.Methods: The group studied ...

A 29-year-old pregnant lady known hypothyroid for 5 years, presented with thyroid eye disease (TED). She is a non-smoker. Her TFT in the past years has been stable.Her exophthalmos was noticed at early pregnancy. Her anti-thyroid peroxidise antibodies (TPO-Ab) were >1300 mU/l (ref. range <1.4) and TSH-R antibodies (TRAB) were 18.6 U/l (ref. range <5.0).On presentation she was clinically and biochemically euthyroid with ...

Introduction: Papillary thyroid carcinoma is characterized by a good prognosis and a slow progression. Its metastases are usually located in cervical lymph nodes. But, sometimes they can reach the lung and bones. Cerebral metastases are exceptional as they have been reported in only 4%. Single or multiple, they can be totally symptomatic, but they are life threatening and require specific care as in the following caseCase report: A man aged 56, was refer...

Subclinical hypothyroidism (SCH) represents a mild or compensated form of primary hypothyroidism. Although the relationship between SH and lipid profile have been reported in several studies, the results are conflicting. The objective of the present study is to assess dyslipidemia among patients with SCH. Our study included 107 patients vs 108 sex matched controls. Clinical information and medical history were obtained through a questionnary from all SCH patients and normal co...

Introduction: Metastases of thyroid carcinoma to the choroid and/or orbit are rare and usually occur at an advanced stage of the disease. The principal symptoms are decreased or blurred vision and/or persistent eye pain but they can be totally asymptomatic. They are diagnosed by ultrasound ocular CT and/or MRI scanning. The diagnosis is certain if they fix radioactive iodine. Their prognosis is very bad. Enucleation is the treatment of choice in cases of visual impairment. We ...

Objective: The objective of this study was to examine the factors influencing the severity of hepatic steatosis in type 2 diabetes.Methods: Computed tomography imaging was used to assess hepatic fat content in 80 men and women with type 2 diabetes. Inclusion criteria included a confirmed diagnosis of type 2 diabetes (≥1 year of duration), without history of hepatic disease or daily consumption of alcohol drink. The ratio of liver to spleen attenuat...

Background and aims: To study the need for insulin during pregnancy, depending on the duration of the disease.Methods: We studied 108 pregnant women with DM 1 receiving insulin with insulin pumps. Patients were divided into three groups: in the 1st group diabetes duration was less than 5 years, in the 2nd – 5 to 15 years, 3rd – more than 15 years. We evaluated the daily need for insulin on 12, 22–25, 30–32 weeks of gestation.<p cl...

Introduction: The metabolic syndrome (MS) is a frequent complication of the obstructive sleep apnea hypopnea syndrome (OSAHS). Its predictive factors have to be known by the doctors setting in charge patients with OSAHS. The aim of this study was to determine the prevalence of the MS and its predictive factors in Tunisian patients with OSAHS.Methods: A retrospective study including 181 patients with OSAHS from the respiratory D department at the Abderrah...

Introduction: Brain metastases of thyroid carcinomas are rare (0.1–5%) according to the literature data. They generally occur in a context of metastatic spread which has a serious impact on survival. We report two cases and will review the literature data.Observations: Case 1: 57-year-old patient monitoring for papillary thyroid carcinoma in its solid form trabecular classified T4N0M1with lung metastases. Following a neurological symptoms of tonic-c...

Introduction: Papillary thyroid carcinoma (PTC) has generally good prognosis, and distant spread is rare. Common sites of distant metastasis are lung parenchyma and bone. Pleural metastasis is less common (0.6%), and most cases have been detected because of pleural effusion. Malignant pleural effusion is a poor prognostic factor among patients with PTC. We report a case of pleural metastasis of PTC proved by pleural biopsy.Case report: A 62-year-old man ...