Endocrine Abstracts

Introduction: PATRO children is an international, non-interventional, longitudinal study of the long-term safety of a biosimilar recombinant human growth hormone (Omnitrope, Sandoz). In particular, the study assesses the diabetogenic potential of Omnitrope and the risk of malignancies. The long-term efficacy is a secondary objective of the study. Here we present safety and efficacy data of UK patients recruited since 2008, following an interim analysis in May 2017.<p class...

Background: Old age is proven to be one of the greatest danger factors for intensively dealing with COVID-19 patients. Stoutness and diabetes are enhancers of dangers among COVID-19 patients. In any case, there exists restricted proof for the modifiable danger components, for example, bodyweight which is an indicator of the Intensive Care Unit and its need among type 2 diabetes patients. In this review, the subject of body weight as an indicator of ICU confirmations will be in...

Background: The consequences of overt hypothyroidism on the central nervous system are well known. Interestingly, there is less proof in regards to the impacts of subclinical hypothyroidism (SCH) on the cognitive functions among elderly subjects. Studies from various countries including India have shown a variable association between SCH and cognitive dysfunction. This study planned to survey the event of cognitive impairment among the older Indian subjects who were introducin...

Introduction: Increase in global childhood obesity is considered to be one of the detrimental problems all across the world. It is well known that about every 1 in every 300-500 infants suffers from Type-1 Diabetes Mellitus. Obesity has been directly associated with elevation of blood sugar and HbA1c.Objective: This study investigates the prevalence of obesity in Type-1 DM and the distribution of sex, age and its correlation with HbA1.<p class="abste...

Introduction: Acute and chronic alcohol intake and alcohol withdrawal induce dysfunction of neuroendocrine and other regulatory systems. The expression ‘neuroendocrine dysfunction’ alludes to an assortment of conditions brought about by imbalances in the body’s chemical creation straightforwardly connected with the pituitary, nerve center, and their tomahawks following TBI.Aims: This study aimed to assess a possible hypothalamo-pituitary-a...

Introduction: According to guidelines, to predict early signs of micro-vascular complications in patients with diabetes, regular foot examination and perform regular investigations which include HbA1c, urea and electrolytes (U+Es), albumin-creatinine ratio (ACR) and lipid profile.Methods: During February 2017, consecutive patient medical notes were collected from a weekly general diabetic clinic. Using the patient notes ...

Introduction: According to guidelines, to predict early signs of micro-vascular complications in patients with diabetes, regular foot examination and perform regular investigations which include HbA1c, urea and electrolytes (U+Es), albumin-creatinine ratio (ACR) and lipid profile.Methods: During February 2017, consecutive patient medical notes were collected from a weekly general diabetic clinic. Using the patient notes ...

Background: Obesity is a global health concern and a recognised risk factor for several prevalent diseases. Genetic variation can influence susceptibility to the development of obesity. Existing work in humans explains a limited proportion of the heritability of obesity-related traits and prioritisation of variants on which to focus mechanistic studies is challenging. Novel insights can be obtained from species such as the domestic dog and the pig in which obesity occurs spont...

Background and Aim: RAIT has a high success rate in achieving cure of hyperthyroidism but there is unpredictability of thyroid status during the initial post-RAI period, making it difficult to counsel patients or plan medical therapy. We assessed the role of updated TRAB level at the time of RAIT in predicting persistent post-RAI hyperthyroidism.Patients and Methods: We measured TRAB at the time of RAIT (fixed 550MBq dose) in 26 patients with Graves&#146...

Introduction: Chronic liver disease (CLD) is usually not described as a common cause of hypercalcemia unless there is hepatoma. Of late, there are some reports suggesting CLD as a cause for hypercalcemia. The exact mechanism contributing to hypercalcemia in CLD is poorly understood. It usually correlates with the severity of disease.Aim of the study: To assess the prevalence of hypercalcemia in patients with chronic liver disease To study the relation of...