Endocrine Abstracts

Introduction: Most common two causes of primary hyperaldosateronism are bilateral idiopathic hyperplasia and aldosteron secreting adenoma but unilateral adrenal hyperplasia is a rare cause. We presented a primary hyperaldosteronism case that caused by unilateral adrenal hyperplasia.Case: A 56-year-old male admitted to endocrinology policlinic with complaints of polydipsia, polyuria, fatigue and muscle wasting. He had hypertension for 4 years. In physical...

Introduction: Autoimmune adrenal injury is the most common cause of primary adrenal failure (PAF) (70–90%). Antiphospholipid syndrome (APS) that characterized by thrombosis and abortus may be a reason of PAF. In this presentation we reported a case of primary adrenal failure due to primary antiphospholipid syndrome.Case: A 34-year-old boy was brought to emergency service due to loss of consciousness. In physical examination patients was confused, bl...

Introduction: Oncocytic (Hurthle cell) carcinoma is consisted of <5% of thyroid cancer but most metastasizing cancer type among differentiated thyroid cancer. We presented an oncocytic carcinoma with sternum metastasis.Case: A 68-year-old women admitted to endocrinology policlinic with complaint of a mass in her neck. She was diagnosed hyperthyroidism and she was using thionamid for 6 months. Her medical history revealed hypertension for 3 years and ...

Aim: Thyroid tissue originates from foramen cecum located in the base of the tongue and with embryonal development it descends through thyroglossal duct to its normal location. A total or partial failure in thyroid tissue descending causes ectopic thyroid tissue. One of this ectopic region is lingual region. We presented two case of ectopic thyroid tissue.Case 1: A 18-year-old female that uses levothyroxine 100 mcg/day for hypothyroidism admitted to endo...

Aim: Diabetes mellitus affects many systems and one of them is skin. Skin findings among diabetic patients reported 30–71%. Skin findings may be due to direct metabolic effects of diabetes but complications and drugs may be cause as well. In this study our aim was to investigate the skin findings and prevalence among diabetic patients that admitted to endocrinology policlinic.Method: 81 patients involved to study, skin examination of the patients we...

Background: X and Y chromosomes carry many genes that direct development and gametogenesis. Rearrangements associated with X chromosome may have a role in abnormal phenotypes. We presented a case of primary amenorrhea with normal karyotype but centromere thickness in 13th chromosome (13 cenh+), this is the first case in literature.Case: A 18-year-old woman admitted to endocrinology clinic with complaints of primary amenorrhea and a failure in ...

Introduction: Wolfram syndrome has characterized by central diabetes insipidus (DI), diabetes mellitus (DM), optic atrophy (OA) and deafness. In this report we presented a Wolfram syndrome with hypergonadotropic hypogonadism.Case: A 18-year-old girl who has diabetes for 6 years was hospitalized due to blood sugar irregularity. Her medical history revealed frequent urination and enuresis for 2–3 years and primary amenorrhea. Furthermore she had hear ...

Aim: Our aim was to investigate the frequency of isolated maternal hypothyroxinemia (IMH) at gestational diabetes mellitus (GDM)Material and method: Fifty women with GDM aged between 20–41 and 100 healthy pregnant aged between 17–41 were involved to study. Patients that have thyroid disease and low free T4 levels at first trimester were ruled out. Thyroid function tests of patients and healthy controls were assessed at first, second ...

Objective: We aimed to evaluate the frequency of malignancy in patients with follicular lesion or follicular neoplasia in cytological examination.Method: About 29 patients who had follicular neoplasia or follicular lesion in cytological examination after ultrasound guided thyroid fine needle aspiration biopsy (FNAB) were included in the study. Histopathologic results were evaluated after thyroidectomy in all patients.Results: There...

Objective: Incidence of concomitant thyroid cancer and Hashimoto thyroiditis (HT) is found to be 0.3–58% in different series. In this study, we aimed to find out HT incidence in thyroid cancer patients in our clinic and we tried to determine ultasonographic and histopathologic features of tumor in these patients.Method: About 165 patients diagnosed with thyroid carcinoma between 2005 and 2008 were included in the study. Patients with Graves’s d...