Searchable abstracts of presentations at key conferences in endocrinology

ea0039ep53 | Diabetes | BSPED2015

Too sweet for too long?

Ali Salma , Khetan Renu , Sachdev Pooja , Bhatt Jayesh

Background: Cystic fibrosis related diabetes (CFRD) is associated with deterioration in clinical status. Lung function and nutritional status deteriorate up to 2–4 years before a diagnosis of CFRD based on the oral glucose tolerance test (OGTT). Timely detection and treatment is crucial.Aims: To evaluate: i) adherence to CFRD screening guidelines and ii) whether identifying stages of progressive cystic fibrosis insulin deficiency (CFID) using the ex...

ea0036P17 | (1) | BSPED2014

Neonatal seizure: a rare presentation of maternal hyperparathyroidism

Dunn Lucy , Ashmore Laura , Randell Tabitha , Denvir Louise , Sachdev Pooja

Introduction: Hypocalcaemia is a recognised cause of neonatal seizures most often related to vitamin D deficiency in the mothers of exclusively breast fed infants. There have also been case reports of an underlying diagnosis of hyperparathyroidism in a reportedly well mother becoming apparent after the infant presents with hypocalcaemic seizures. Maternal hypercalcaemia suppresses parathyroid activity in the foetus, which causes transient neonatal hypocalcaemia.<p class="a...

ea0036P27 | (1) | BSPED2014

Children with type 1 diabetes and coeliac disease at Nottingham Children's Hospital: a service review and evaluation

Ashcroft Jennifer , Randell Tabitha , Denvir Louise , Sachdev Pooja

Introduction: The prevalence of coeliac disease (CD) in type 1 diabetes (T1DM) is 4.4–11.1 vs 0.5% in the general population. The compliance to gluten free diet (GFD) in symptomatic patients vs those diagnosed on screening is significantly higher as expected. The impact of untreated CD on patients with T1DM ranges from malabsorption and frequent unexplained hypoglycaemia to no symptoms.Aims: i) To describe the demographics of our children with CD.</...

ea0036P47 | (1) | BSPED2014

An ovulating testis

Gopal-Kothandapani Jaya Sujatha , Sachdev Pooja , Wright Neil

Introduction: Ovotesticular disorders of sexual development (DSD) are a rare form of DSD with co-existence of both ovarian and testicular tissue in one or both gonads.Case report: A term infant (weight+1.38 SDS) presented at birth with severe penoscrotal hypospadias, a small phallus and a right hemiscrotum with descended gonad (external masculinization score 1.5). Pelvic ultrasound revealed no mullerian structures, a small right gonad with probable epidi...

ea0036P50 | (1) | BSPED2014

Sex chromosome mosaicism in males: our experience

Santhanam Priyha , Sachdev Pooja , Denvir Louise , Randell Tabitha

Introduction: 45XO/46XY karyotype has varied phenotypic spectrum ranging from short stature, ambiguous genitalia (60%), clinical signs of Turner’s syndrome in both males and females and normal male phenotype. We report six phenotypically male cases with a varied clinical presentation.Case 1 and 2: Short stature: Two pre-pubertal, phenotypical males, were referred with concerns regarding short stature (height <0.4th centile, height velocity &#150...

ea0058p057 | Diabetes | BSPED2018

Type 1 diabetes cohort with HbA1c ≤ 48 mmols/mol April 2017 – March 2018 – what have we learnt?

Saddington Caroline , Sachdev Pooja , Randell Tabitha , Denvir Louise

Background: 71/270 (26%) of our patients with T1DM, diagnosed for more than 1 year, had an ideal HbA1c of less than or equal to 48 mmol/mol. Are there factors within this group that may be transferred into groups with higher HbA1cs to improve control?Methods: Clinical records were reviewed for the whole year and download data from a randomly selected 2 week period was reviewed. Age, gender, time from diagnosis, ethnicity, postcode, other medical conditio...

ea0058p072 | Diabetes | BSPED2018

A diabetes transition programme: outcomes and scope for improvement

Paice Bronte , Drew Josephine , Randell Tabitha , Sachdev Pooja , Calvert Jennifer

Introduction: ‘Transition’ is the period of movement from paediatric to adult healthcare. These patients are in their adolescence when the brain is maturing, causing changes in behaviors including greater risk-taking. The period of transition can be associated with poor adherence to insulin and blood glucose monitoring regimens and an increased risk of diabetic ketoacidosis (DKA). This study looks into how effective our transition programme has been at addressing thi...

ea0033oc3.6 | Oral Communications 3 | BSPED2013

A feasibility study of intra-gastric balloons (supported by a lifestyle programme) for the treatment of severe adolescent obesity – the (BOB) Study.

Sachdev Pooja , Reece Lindsey , Copeland Rob , Wales Jerry , Wright Neil

Rationale: Although many adolescents meet the NICE criteria for bariatric surgery there is a reluctance to undertake or commission such irreversible procedures in young people. Balloons are temporary, reversible, safer and more acceptable and in adults have been shown to promote a clinically significant change in BMI of 4.0–9.0 kg/m2 But due to subsequent weight regain, bypass surgery is preferred.This is a feasibility study of endocsopic...

ea0027p67 | (1) | BSPED2011

Clinic appointment reminders and their effect on ‘did not attend' (DNA) rates and HbA1C, in a paediatric diabetes clinic

Sachdev Pooja , Gunn Elaine , Harron Katie , Natarajan Anuja

Background: Non-attendance in outpatient clinics results in administrative problems, economic loss and poor patient care. Mobile phone intervention has been shown to be effective in improving attendance rates in chronic disease follow up. A pilot study conducted over 9 months in our diabetes clinic showed improved attendance following phone calls and text messages sent to carers/young people prior to their clinic appointment (statistical significance reached when patient spoke...

ea0023p20 | (1) | BSPED2009

Synacthen tests in children with asthma on high dose inhaled corticosteroids

Avatapalle Hima Bindu , Sachdev Pooja , Wright Neil , Elder Charlie

Background: Adrenal suppression is a well recognised complication of inhaled corticosteroids. Committee for Safety of Medicines (CSM) guidelines (2006) recommend that children taking high dose inhaled corticosteroids (HDICS) are tested for adrenal insufficiency. Patients requiring steroid replacement require a steroid card and written advice on steroid replacement in acute illness.Aims: To determine the impact of CSM guidelines on the use of short synact...