Searchable abstracts of presentations at key conferences in endocrinology

ea0056p123 | Endocrine tumours and neoplasia | ECE2018

Hormonal secretion prevalence in a series of subjects with adrenal tumors incidentally discovered in clinical practice

Barbu Carmen Gabriela , Pienary Adrian Teodor , Albu Alice , Martin Sorina , Sirbu Anca , Florea Suzana , Fica Simona

The objective of the study was to evaluate the prevalence of secreting profile among a series of subjects with incidental discovered adrenal tumors. Subjects. 139 subjects (112 women and 27 men) diagnosed with adrenal tumors between 2010 and 2015 in our department.Methods: Medical records were retrospectively analysed for demographic data, routine tests, specific adrenal hormones measurements, associated diseases.Results: Regarding...

ea0056p151 | Neuroendocrinology | ECE2018

A rare association of neuroendocrine tumors

Pascu Raluca Cristina , Soare Iulia , Mazalu Liliana , Sirbu Anca Elena , Fica Simona

Background: The occurrence of multiple endocrine tumors in the same patient is not always typical and cannot always be classified into a multiple endocrine neoplasia (MEN) type, McCune-Albright syndrome or the Carney complex. Schwannomas are mesenchymal tumors that originate from Schwann cells of peripheral nerve fibers that can associate in some syndromes. 90% cases are benign, involving usually the head, neck and extremities. They are rare in the retroperitoneal region (1&#1...

ea0056p575 | Obesity | ECE2018

The effect of laparoscopic sleeve gastrectomy on kidney function

Leca Bianca , Sava Elisabeta , Soare Iulia , Martin Sorina , Smeu Bogdan , Copaescu Catalin , Sirbu Anca , Fica Simona

Introduction: Higher body mass index (BMI) has been associated with adverse renal outcomes, including chronic kidney disease (CKD), progression to end-stage renal disease (ESRD), nephrolithiasis and renal cell cancer. Several studies have shown that weight loss following bariatric surgery has a positive effect on kidney function, mediated by a reduction in proteinuria, glomerular hyperfiltration and improvements in blood pressure and insulin resistance. The aim of this study w...

ea0056p577 | Obesity | ECE2018

Weight loss and metabolic parameters after laparoscopic sleeve gastrectomy

Sava Elisabeta , Leca Bianca , Sirbu Anca , Soare Iulia , Martin Sorina , Smeu Bogdan , Copaescu Catalin , Fica Simona

Introduction: Obesity, defined as a BMI ≥30 kg/m2, is the most common chronic metabolic disease in the world and its prevalence has strongly increased. Obesity is associated with multiple comorbidities, including cardiovascular disease, hypertension, insulin resistance, dyslipidemia, type 2 diabetes, sleep apnea and certain cancers. Bariatric surgery is the most effective treatment for severe obesity and produces dramatic and durable weight loss. The ...

ea0092ps2-14-07 | Case Reports 1 | ETA2023

Primary thyroid mucoepidermoid carcinoma with extensive pulmonary metastasis

Sirbu Anca , Martin Sorina , Terzea Dana , Voda Claudia , Burga Alexandra , Fica Simona

Mucoepidermoid carcinomas (MECs) are the most common malignant tumors of the salivary glands. Primary thyroid MECs are extremely rare (about 0.5% of all thyroid malignancies) and, in the majority of cases, are associated with an indolent biologic potential and excellent long-term prognosis. We present the case of a 67-year-old man, with a recently growing anterior cervical mass, associating dyspnoea and fatigue. Thyroid ultrasound revealed an inhomogeneous, hypoechoic mass in ...

ea0099ep384 | Pituitary and Neuroendocrinology | ECE2024

Endocrinologic evaluation in a case series of adult meningiomas: what can we improve?

Nacu Miruna-Viorela , Martin Sorina , Sirbu Anca , Barbu Carmen , Fica Simona

Introduction: Meningiomas, already one of the most frequent types of primary central nervous system tumors, have been increasing in incidence in the past decade. Considering their location and histologic particularities, radiation therapy (RT), alone or in combination with neurosurgery, is often necessary and can have a negative impact on adjacent structures such as the pituitary gland. More studies investigating the endocrinologic disturbances in this pathology are necessary ...

ea0090p81 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Early impact of bariatric surgery on obesity-related kidney dysfunction

Maria Popa Miruna , Sirbu Anca , Malinici Elisabeta , Sorina Martin Carmen , soare iulia , Gabriela Barbu Carmen , Copaescu Catalin , Fica Simona

Background: Renal dysfunction is known to be more prevalent amongst patients with obesity. Metabolic and bariatric surgery is associated with positive renal effects through intricate pathways. We aimed to determine the short-term impact of laparoscopic sleeve gastrectomy (LSG) on renal function and to identify parameters associated with its variation.Materials and methods: We performed a retrospective study on 268 patients (115 males and 153 females) eva...

ea0090ep785 | Pituitary and Neuroendocrinology | ECE2023

Acromegaly and metabolic comorbidities – a retrospective study

Dumitras Teodor , Duta Simona Gabriela , Calapod Ruxandra , Bancu Alexandra , Nistor Irina , Sirbu Anca , Martin Sorina , Barbu Carmen , Fica Simona

Introduction: Acromegaly is a rare endocrine disease characterised by excess GH produced by a pituitary adenoma. It is associated with several complications and comorbidities. Metabolic alterations such as diabetes and dyslipidemia are quite frequent described in these patients.Materials and methods: This is a retrospective observational cross-sectional study meant to assess the metabolic modifications in a group of acromegaly patients evaluated in our d...

ea0065p419 | Thyroid | SFEBES2019

Postoperative hypoparathyroidism in patients after total thyroidectomy – experience of a tertiary center in Romania

Martin Carmen Sorina , Andrei Marian , Parfeni Ovidiu , Sirbu Anca , Barbu Carmen , Giulea Cosmin , Miron Adrian , Andrei Florin , Fica Simona

Objectives: Post-surgical hypoparathyroidism (PoSH) is a common long-term complication after thyroid surgery. The reported median incidence rates of temporary and permanent PoSH was 27% and 1% respectively.Methods and results: We retrospectively analyzed the files of 552 patients who underwent thyroidectomy in our surgery department between 2015 and 2017 with the aim to assess the prevalence of PoSH and to identify patient and disease related factors ass...

ea0049ep947 | Pituitary - Clinical | ECE2017

Long-term outcomes of medical therapy in patients with acromegaly: a retrospective analysis

Soare Iulia Simona , Betivoiu Minodora Andreea , Martin Sorina Carmen , Sirbu Anca Elena , Barbu Carmen Gabriela , Albu Alice Ioana , Fica Simona

Background: Acromegaly is a rare severe disease which, untreated, leads to increased cardiovascular and respiratory morbidity and mortality. Pituitary surgery is the first-line therapy, and medical treatment (somatostatin receptor ligands SRLs, dopamine agonists DA, and GH receptor antagonists GHRAs) is indicated for persistent disease. While selected patients are treated with DA and GHRAs, SRLs remain the mainstay of acromegaly therapy.Objective: The ai...