ea0035p8 | Adrenal cortex | ECE2014
Reimondo Giuseppe
, Coletta Marcella
, Giachino Daniela
, Chiodini Iacopo
, Kastelan Darko
, Morelli Valentina
, Cannavo Salvatore
, Cuccurullo Alessandra
, Beck-Peccoz Paolo
, De Marchi Mario
, Terzolo Massimo
Introduction: Some variants of the glucocorticoid receptor (GR) gene have been found to alter glucocorticoid sensitivity and have been associated with worsen metabolic profiles.Objective: The aims of the present study were: i) to examine whether the prevalence of N363S, ER22/23EK and BclI variants was different in patients with adrenal incidentaloma (AI) and/or subclinical Cushings syndrome (SCS) than control subjects and ii) whether the presence o...