Endocrine Abstracts

Introduction: Central diabetes insipidus (DI) is observed in up to 34% of patients undergoing pituitary surgery. Early postoperative diagnosis of DI is critical because its detection allows early treatment, reducing morbidity and hospital stay. AVP levels measurement is not commonly used to diagnose DI. As an alternative, copeptin determination has been proposed, but its usefulness has only been validated in one series.Objective: To define the threshold ...

Introduction: Resistance to thyroid hormones (RTH) is a genetic disorder caused in 85% of cases by mutations in thyroid hormone receptor beta gene (TRβ). The current information about it in Spanish population is scarce, limited to case reports or short series of patients. Thus, we aimed to describe the clinical, biochemical and genetic features of Mediterranean patients with RTH referred to our institution (one of the referral centres in Spain) for genetic testing during ...