ea0090ep28 | Adrenal and Cardiovascular Endocrinology | ECE2023
Casals Gregori
, Ballesteros Maria Antonieta
, Zamora Angielys
, Martinez Irene
, Ruiz Montserrat
, Fernandez-Varo Guillermo
, Mora Mireia
, Morales-Ruiz Manuel
, Hanzu Felicia A
Introduction: Urine free cortisol measurements are routinely performed to evaluate hypercortisolism. Despite their analytical inaccuracy, immunoassay-based methods are frequently used. Advances in liquid chromatography high resolution mass spectrometry (LC-HRMS) facilitate the incorporation of powerful diagnostic tools into clinical laboratories with high analytical specificity that also allow simultaneous quantification of different metabolites and untargeted compound identif...