Endocrine Abstracts

Introduction: The demand of cortisol rises during stress and to avoid acute cortisol deficiency, patients undergoing transsphenoidal surgery at Skåne University Hospital (Sweden) receive peri- and postoperative substitution with hydrocortisone (HC), even at normal ACTH function. Some anesthetics are known to affect cortisol levels.This study aimed to assess the perioperative cortisol plasma levels during transsphenoidal surgery in ACTH sufficient an...

Background: Due to the rarity and the slow progress of the disease, there is a considerable diagnostic delay in acromegaly, contributing to increased morbidity and mortality. Voice analysis may decrease this delay as patients with acromegaly often develop a dark voice and unclear speech due to macroglossia, enlarged lips and edema in the pharynx and larynx. Modern technology offers higher speed and power of voice analysis and increased the interest in voice as a biomarker to i...