ea0020p126 | Thyroid | ECE2009
Pitrone Maria
, Zito Giovanni
, Carissimi Elvira
, Bommarito Alessandra
, Richiusa Pierina
, Galluzzo Aldo
, Giordano Carla
, Pizzolanti Giuseppe
, Bullara V
Anaplastic thyropid carcinoma (ATC) is one of the most aggressive endocrine tumors with morphological features of undifferentiated neoplasm. Patients with ATC have a poor prognosis with a mean survival time of 26 months. Surgery, radiotherapy and chemotherapy do not improve survival rate. Bisphosphonates, analogs of endogenous pyrophosphates in which a carbon atom replaces the central oxygen atom, are successful agents for the prevention and treatment of postmenopausal o...